Transcription Factor

Accessions: 4xlp_F (3D-footprint 20231221)
Names: RNA polymerase sigma factor SigA, SIGA_THEAQ
Organisms: Thermus aquaticus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q9EZJ8
Length: 345
Pfam Domains: 1-35 Sigma-70 factor, region 1.2
109-179 Sigma-70 region 2
188-266 Sigma-70 region 3
279-331 Sigma-70, region 4
Sequence:
(in bold interface residues)
1 DPVRQYLHEIGQVPLLTLEEEIDLARKVEEGMEAIKKLSEATGLDQELIREVVRAKILGT 60
61 ARIQKIPGLKEKPDPKTVEEVDGKLKSLPKELKRYLHIAREGEAARQHLIEANLRLVVSI 120
121 AKKYTGRGLSFLDLIQEGNQGLIRAVEKFEYKRRFKFSTYATWWIRQAINRAIADQARTI 180
181 RIPVHMVETINKLSRTARQLQQELGREPSYEEIAEAMGPGWDAKRVEETLKIAQEPVSLE 240
241 TPIGDEKDSFYGDFIPDENLPSPVEAAAQSLLSEELEKALSKLSEREAMVLKLRKGLIDG 300
301 REHTLEEVGAYFGVTRERIRQIENKALRKLKYHESRTRKLRDFLE
Interface Residues: 305, 306, 315, 316, 317, 318, 320, 321
3D-footprint Homologues: 3n97_A, 6ido_B, 8cyf_B
Binding Motifs: 4xlp_F CTTGAcannnnnnnnnnnnTnTGCT
Binding Sites: 4xlp_O
4xlp_P
Publications: Bae B, Feklistov A, Lass-Napiorkowska A, Landick R, Darst SA. Structure of a bacterial RNA polymerase holoenzyme open promoter complex. Elife : (2015). [Pubmed]
Related annotations: PaperBLAST

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