Transcription Factor

Accessions: 6y42_A (3D-footprint 20231221), 6y42_B (3D-footprint 20231221)
Names: F2RGC9_STRVP, Rrf2 family transcriptional regulator
Organisms: strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745, Streptomyces venezuelae
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: F2RGC9
Length: 159
Pfam Domains: 1-80 Transcriptional regulator
20-71 Winged helix-turn-helix transcription repressor, HrcA DNA-binding
Sequence:
(in bold interface residues)
1 KLSGGVEWALHCCVVLTAASRPVPAARLAELHDVSPSYLAKQMQALSRAGLVRSVQGKTG 60
61 GYVLTRPAVEITLLDVVQAVDGPDPAFVCTEIRQRGPLATPPEKCTKACPIARAMGAAEA 120
121 AWRASLAATTIADLVATVDDESGPDALPGVGAWLIEGLG
Interface Residues: 35, 36, 37, 38, 40, 41, 44, 48, 56, 58
3D-footprint Homologues: 6za3_B, 4hf1_A, 7b0c_A, 6y42_B
Binding Motifs: 6y42_AB ACTcGGATAnnnnnTGTCCGAG
6y42_B CTCGGACA
Binding Sites: 6y42_E
6y42_F
Publications: Crack JC, Amara P, Volbeda A, Mouesca JM, Rohac R, Pellicer Martinez MT, Huang CY, Gigarel O, Rinaldi C, Le Brun NE, Fontecilla-Camps JC. Electron and Proton Transfers Modulate DNA Binding by the Transcription Regulator RsrR. J Am Chem Soc 142:5104-5116 (2020). [Pubmed]
Related annotations: PaperBLAST

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