Transcription Factor
| Accessions: | ZNF771 (HT-SELEX2 May2017) |
| Names: | ENSG00000179965, ZNF771 |
| Organisms: | Homo sapiens |
| Libraries: | HT-SELEX2 May2017 1 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Notes: | TF family: Znf_C2H2 experiment: HT-SELEX Hamming distance: 2 cycle: 2, TF family: Znf_C2H2 experiment: HT-SELEX Hamming distance: 2 cycle: 3, TF family: Znf_C2H2 experiment: Methyl-HT-SELEX Hamming distance: 2 cycle: 2, TF family: Znf_C2H2 experiment: Methyl-HT-SELEX Hamming distance: 2 cycle: 3 |
| Length: | 259 |
| Pfam Domains: | 20-42 C2H2-type zinc finger 20-38 C2H2-type zinc finger 20-42 Zinc finger, C2H2 type 35-58 Zinc-finger double domain 48-66 C2H2-type zinc finger 49-70 Zinc finger, C2H2 type 50-70 C2H2-type zinc finger 62-86 Zinc-finger double domain 75-98 C2H2-type zinc finger 76-98 C2H2-type zinc finger 76-98 Zinc finger, C2H2 type 90-114 Zinc-finger double domain 104-126 Zinc finger, C2H2 type 104-126 C2H2-type zinc finger 104-126 C2H2-type zinc finger 118-141 Zinc-finger double domain 132-154 C2H2-type zinc finger 132-154 C2H2-type zinc finger 132-154 Zinc finger, C2H2 type 147-170 Zinc-finger double domain 160-182 C2H2-type zinc finger 160-182 C2H2-type zinc finger 160-182 Zinc finger, C2H2 type 174-199 Zinc-finger double domain 187-210 C2H2-type zinc finger 188-210 C2H2-type zinc finger 188-210 Zinc finger, C2H2 type 202-225 Zinc-finger double domain 216-238 C2H2-type zinc finger 216-240 C2H2-type zinc finger 216-238 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 DNKEVPGEAPAPSADPARPHACPDCGRAFARRSTLAKHARTHTGERPFGCTECGRRFSQK 60 61 SALTKHGRTHTGERPYECPECDKRFSAASNLRQHRRRHTGEKPYACAHCGRRFAQSSNYA 120 121 QHLRVHTGEKPYACPDCGRAFGGSSCLARHRRTHTGERPYACADCGTRFAQSSALAKHRR 180 181 VHTGEKPHRCAVCGRRFGHRSNLAEHARTHTGERPYPCAECGRRFRLSSHFIRHRRAHMR 240 241 RRLYICAGCGRDFKLPPGA |
| Interface Residues: | 30, 31, 33, 34, 37, 58, 59, 60, 61, 62, 64, 65, 67, 68, 69, 71, 86, 87, 88, 89, 90, 92, 93, 97, 114, 115, 116, 117, 118, 119, 120, 121, 132, 142, 143, 144, 145, 146, 148, 149, 150, 170, 171, 172, 173, 174, 175, 177, 178, 179, 198, 199, 200, 201, 202, 204, 205, 211, 225, 227, 228, 229, 230, 232, 233, 237, 254 |
| 3D-footprint Homologues: | 7y3l_A, 1tf3_A, 5k5l_F, 8ssu_A, 1tf6_A, 5v3j_F, 2i13_A, 8gn3_A, 5kkq_D, 5yel_A, 1f2i_J, 6wmi_A, 8ssq_A, 7w1m_H, 5und_A, 7y3m_I, 7ysf_A, 1ubd_C, 3uk3_C, 8cuc_F, 6blw_A, 2wbs_A, 7txc_E, 5yj3_D, 5k5i_A, 2gli_A, 2lt7_A, 2jpa_A, 1g2f_F, 6ml4_A, 4x9j_A, 1mey_C, 5kl3_A, 1llm_D, 6e94_A, 2kmk_A, 7n5w_A, 6u9q_A, 5ei9_F, 7eyi_G, 8h9h_G, 4m9v_C, 6jnm_A, 6a57_A, 2drp_D |
| Binding Motifs: | ZNF771_2 drCGCTAACCAYTry ZNF771_4 drCGCTAACCAyTry ZNF771_methyl_1 tgCGCTAACCAYTry ZNF771_methyl_3 yrCgCTAACCAyTrc |
| Related annotations: | PaperBLAST |
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