Transcription Factor

Accessions: JUND (HT-SELEX2 May2017)
Names: ENSG00000130522, JUND
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Notes: TF family: bZIP experiment: HT-SELEX Hamming distance: 1 cycle: 4, TF family: bZIP experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 4
Length: 140
Pfam Domains: 2-50 Jun-like transcription factor
58-121 bZIP Maf transcription factor
59-121 bZIP transcription factor
64-119 Basic region leucine zipper
Sequence:
(in bold interface residues)
1 GGAATVAFAAEPVPFPPPPPPGALGPPRLAALKDEPQTVPDVPSFGESPPLSPIDMDTQE 60
61 RIKAERKRLRNRIAASKCRKRKLERISRLEEKVKTLKSQNTELASTASLLREQVAQLKQK 120
121 VLSHVNSGCQLLPQHQVPAY
Interface Residues: 67, 70, 71, 72, 74, 75, 78, 79, 82
3D-footprint Homologues: 2wt7_A, 1gd2_G, 2wt7_B, 7x5e_F, 1skn_P, 2dgc_A, 5vpe_C, 1dh3_C, 5vpe_D, 5t01_B
Binding Motifs: JUND_3 srTGACGTCAts
JUND_4 srTGACGCAys
JUND_methyl_1 gATGAsTCATs
JUND_methyl_2 saTGACtCATs
Related annotations: PaperBLAST

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