Transcription Factor

Accessions: T061524_1.02 (CISBP 1.02)
Names: slr-2, T061524_1.02;
Organisms: Caenorhabditis elegans
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:C2H2 ZF
Length: 426
Pfam Domains: 61-82 Zinc-finger double domain
Sequence:
(in bold interface residues)
1 MSKSEHFVSKENWQHLIMKPGPSNLALPTTQKFRQTSNGRTMKQTWTCGVCRKELSSKRS 60
61 YTEHMNIHNKSRPFQCEHCVYAAASQMTLHRHKLRNHTPKAEWGYRCPYCDDAYMEPAGY 120
121 QQHVQQRHPGLSATYGCPFRICKFTSKSQRHFREHLVKHDRSDKIEEGVDPCALSNQQLV 180
181 RYMVLDEMGIGFQRGYTSYSSSSGASSKPPTVTIRARTNVTIAPKIQGVVTSSQPPPVVI 240
241 CRNDEPKIVWHLEKMCNKKEDISRGNPVSIPPQRLLTHHPPPPQSTRYYVSSHATSSSVT 300
301 SLHNTSTSSLMTSSTTYVEPLPQTYSEINPEFECEADEDDDYLMEAGEAGEAEAEEEEEE 360
361 AENDVIEGEYEDDGPPVLESFGNVSIQQPIQHLIMMEEQWSEDEVASSPTADGSVFPNGL 420
421 IDEELD
Interface Residues: 29, 30, 31, 32, 34, 35, 38, 41, 46, 56, 57, 58, 59, 60, 62, 63, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 115, 116, 117, 118, 119, 120, 121, 122, 126, 146, 147, 148, 149, 151, 154, 155, 158
3D-footprint Homologues: 8ssu_A, 5kkq_D, 8ssq_A, 7w1m_H, 7ysf_A, 1ubd_C, 2kmk_A, 3uk3_C, 7y3l_A, 7n5w_A, 8cuc_F, 1llm_D, 8gn3_A, 4x9j_A, 6u9q_A, 1mey_C, 7txc_E, 5ei9_F, 2gli_A, 1f2i_J, 6wmi_A, 5und_A, 1g2f_F, 8h9h_G, 7eyi_G, 7y3m_I, 2lt7_A, 6e94_A, 2i13_A, 6ml4_A, 2wbs_A, 5k5l_F, 5yel_A, 5yj3_D, 5k5i_A, 1tf6_A, 5v3j_F, 2drp_D
Binding Motifs: M0497_1.02 TTGyAGTy
Related annotations: PaperBLAST

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