Transcription Factor

Accessions: 2ql2_C (3D-footprint 20231221)
Names: Immunoglobulin enhancer-binding factor E12/E47, TCF-3, TFE2_MOUSE, Transcription factor 3, Transcription factor A1, Transcription factor E2-alpha
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P15806
Length: 58
Pfam Domains: 1-52 Helix-loop-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 RRMANNARERVRVRDINEAFRELGRMCQLHLKSDQTKLLILQQAVQVILGLEQQVRER
Interface Residues: 2, 5, 6, 8, 9, 10, 12, 13, 21, 25, 26
3D-footprint Homologues: 7z5k_B, 2ypa_A, 6od3_F, 2ql2_D, 2ypa_B, 2ql2_A, 1dct_B
Binding Motifs: 2ql2_CD CCAGntGG
Publications: Longo A, Guanga G.P, Rose R.B. Crystal structure of E47-NeuroD1/beta2 bHLH domain-DNA complex: heterodimer selectivity and DNA recognition. Biochemistry 47:218-29 (2008). [Pubmed]
Related annotations: PaperBLAST

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