Transcription Factor
| Accessions: | 5t7x_B (3D-footprint 20231221) |
| Names: | EBNA-1, EBNA1_EBVG, EBV nuclear antigen 1, Epstein-Barr nuclear antigen 1 |
| Organisms: | Epstein-Barr virus (strain GD1) (HHV-4), Human herpesvirus 4 |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | Q3KSS4 |
| Length: | 149 |
| Pfam Domains: | 3-148 Epstein Barr virus nuclear antigen-1, DNA-binding domain |
| Sequence: (in bold interface residues) | 1 RKKGGWFGKHRGQGGSNPKFENIAEGLRVLLARSHVERTTEEGNWVAGVFVYGGSKTSLY 60 61 NLRRGIALAVPQCRITPLSRLPFGMAPGPGPQPGPLRESIVCYFMVFLQTHIFAEVLKDA 120 121 IKDLVMIKPAPTCNIKVTVCSFDDGVDLP |
| Interface Residues: | 3, 6, 7, 11, 19, 56, 57, 60, 61, 64 |
| 3D-footprint Homologues: | 5t7x_B, 7u1t_B |
| Binding Motifs: | 5t7x_AB GGATAGCnnntGcTACCC 5t7x_B GGATAgc |
| Binding Sites: | 5t7x_C 5t7x_D |
| Publications: | Dheekollu J, Malecka K, Wiedmer A, Delecluse HJ, Chiang AK, Altieri DC, Messick TE, Lieberman PM. Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency. Oncotarget 8:7248-7264 (2017). [Pubmed] |
| Related annotations: | PaperBLAST |
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