Transcription Factor

Accessions: Q9UGU5 (JASPAR 2024)
Names: High mobility group protein 2-like 1, HMG box-containing protein 4, HMG domain-containing protein 4, HMGX4_HUMAN, Protein HMGBCG
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q9UGU5
Length: 601
Pfam Domains: 107-233 Domain of unknown function (DUF4171)
406-468 Domain of unknown function (DUF1898)
408-470 HMG (high mobility group) box
Sequence:
(in bold interface residues)
1 MAYDDSVKKEDCFDGDHTFEDIGLAAGRSQREKKRSYKDFLREEEEIAAQVRNSSKKKLK 60
61 DSELYFLGTDTHKKKRKHSSDDYYYGDISSLESSQKKKKKSSPQSTDTAMDLLKAITSPL 120
121 AAGSKPSKKTGEKSSGSSSHSESKKEHHRKKVSGSSGELPLEDGGSHKSKKMKPLYVNTE 180
181 TLTLREPDGLKMKLILSPKEKGSSSVDEESFQYPSQQATVKKSSKKSARDEQGALLLGHE 240
241 LQSFLKTARKKHKSSSDAHSSPGPEGCGSDASQFAESHSANLDLSGLEPILVESDSSSGG 300
301 ELEAGELVIDDSYREIKKKKKSKKSKKKKDKEKHKEKRHSKSKRSLGLSAVPVGEVTVTS 360
361 GPPPSIPYAGAAAPPLPLPGLHTDGHSEKKKKKEEKDKERERGEKPKKKNMSAYQVFCKE 420
421 YRVTIVADHPGIDFGELSKKLAEVWKQLPEKDKLIWKQKAQYLQHKQNKAEATTVKRKAS 480
481 SSEGSMKVKASSVGVLSPQKKSPPTTMLLPASPAKAPETEPIDVAAHLQLLGESLSLIGH 540
541 RLQETEGMVAVSGSLSVLLDSIICALGPLACLTTQLPELNGCPKQVLSNTLDNIAYIMPG 600
601 L
Interface Residues: 391, 393, 395, 398, 408, 409, 412, 414, 415, 418, 422, 433, 434, 435, 438, 474, 478
3D-footprint Homologues: 2gzk_A, 1qrv_A, 4s2q_D, 1j5n_A, 3f27_D, 4y60_C, 1o4x_B, 3tmm_A, 7m5w_A, 3u2b_C, 1hry_A, 1ckt_A
Binding Motifs: UN0310.1 rsbAGGGGGCGsb
Binding Sites: UN0310.1.1
UN0310.1.10
UN0310.1.11
UN0310.1.12
UN0310.1.13
UN0310.1.14
UN0310.1.15
UN0310.1.16
UN0310.1.17
UN0310.1.18
UN0310.1.19
UN0310.1.2
UN0310.1.20
UN0310.1.3
UN0310.1.4
UN0310.1.5
UN0310.1.6
UN0310.1.7
UN0310.1.8
UN0310.1.9
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.