Transcription Factor
| Accessions: | PTF1A (HT-SELEX2 May2017) |
| Names: | ENSG00000168267, PTF1A |
| Organisms: | Homo sapiens |
| Libraries: | HT-SELEX2 May2017 1 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Notes: | TF family: bHLH experiment: HT-SELEX Hamming distance: 1 cycle: 3, TF family: bHLH experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 3 |
| Length: | 118 |
| Pfam Domains: | 29-79 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 RLRGLSGAAAAAARRRRRVRSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYE 60 61 KRLSKVDTLRLAIGYINFLSELVQADLPLRGGGAGGCGGPGGGGRLGGDSPGSQAQKV |
| Interface Residues: | 29, 32, 33, 35, 36, 37, 39, 40, 65 |
| 3D-footprint Homologues: | 7z5k_B, 2ypa_A, 7d8t_A, 5i50_B, 1am9_A, 7rcu_E, 6g1l_A, 4h10_A, 6od3_F, 5eyo_A, 8osl_P, 2ypa_B, 2ql2_A, 2ql2_D, 7ssa_L |
| Binding Motifs: | PTF1A_2 gyGTCAGCTGTT PTF1A_methyl_1 ryGTCAGCTGtt |
| Related annotations: | PaperBLAST |
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