Transcription Factor

Accessions: Q8VDK3 (JASPAR 2024)
Names: E74-like factor 5, ELF5_MOUSE, ETS-related transcription factor Elf-5
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 253
Pfam Domains: 37-118 Sterile alpha motif (SAM)/Pointed domain
162-243 Ets-domain
Sequence:
(in bold interface residues)
1 MLDSVTHSTFLPNASFCDPLMPWTDLFSNEDYYPAFEHQTACDSYWTSVHPEYWTKRHVW 60
61 EWLQFCCDQYKLDANCISFCHFNISGLQLCSMTQEEFIEAAGICGEYLYFILQNIRSQGY 120
121 SFFNDAEETKTGIKDYADSSCLKTSGIKSQDCHSRTSLQSSHLWEFVRDLLLSPEENCGI 180
181 LEWEDREQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTGILERVDRRLVYK 240
241 FGKNAHGWQEEKL
Interface Residues: 215, 216, 218, 219, 220, 222, 223, 236
3D-footprint Homologues: 1dux_F, 7jsa_J, 3zp5_A, 8ee9_F, 4mhg_A, 2stt_A, 4uno_A, 3jtg_A, 4l18_B, 4lg0_B, 1yo5_C, 4bqa_A, 1awc_A, 4iri_A, 1bc8_C
Binding Motifs: MA0136.3 rgAAGGAAGTrr
MA0136.4 AAGGAAGT
Binding Sites: MA0136.4.10
MA0136.4.13 / MA0136.4.14
MA0136.4.18
MA0136.3.1 / MA0136.3.2
MA0136.3.10 / MA0136.3.14
MA0136.3.11 / MA0136.3.16
MA0136.3.12
MA0136.3.13 / MA0136.3.19
MA0136.3.14 / MA0136.3.20
MA0136.3.15
MA0136.3.16
MA0136.3.17
MA0136.3.18
MA0136.3.19
MA0136.3.2
MA0136.3.20
MA0136.3.3 / MA0136.3.4
MA0136.3.4 / MA0136.3.5
MA0136.3.5 / MA0136.3.6
MA0136.3.6
MA0136.3.7
MA0136.3.12 / MA0136.3.8
MA0136.3.9
MA0136.3.1
MA0136.3.10
MA0136.3.11
MA0136.3.13
MA0136.3.15
MA0136.3.17
MA0136.3.18
MA0136.3.3
MA0136.3.8
MA0136.3.9
MA0136.4.1 / MA0136.4.5 / MA0136.4.7 / MA0136.4.8
MA0136.4.11
MA0136.4.12
MA0136.4.15 / MA0136.4.16
MA0136.4.17
MA0136.4.19
MA0136.4.2
MA0136.4.20
MA0136.4.3
MA0136.4.4
MA0136.4.6
MA0136.4.9
Publications: Wei G-H, Badis G, Berger MF, Kivioja T, Palin K, Enge M, Bonke M, Jolma A, Varjosalo M, Gehrke AR, Yan J, Talukder S, Turunen M, Taipale M, Stunnenberg HG, Ukkonen E, Hughes TR, Bulyk ML, Taipale J. Genome-wide analysis of ETS family DNA-binding in vitro and in vivo. The EMBO Journal. Epub 2010 Jun 1. doi:10.1038/emboj.2010.106 [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.