Transcription Factor

Accessions: ZNF713_full (HumanTF 1.0)
Names: ZN713_HUMAN, ZNF713
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: Q8N859
Notes: Ensembl ID: ENSG00000178665; Full protein sequence; TF family: znfC2H2; Clone source: Megaman
Length: 431
Pfam Domains: 19-59 KRAB box
268-283 Zinc-finger double domain
272-293 C2H2-type zinc finger
273-295 Zinc finger, C2H2 type
273-295 C2H2-type zinc finger
288-311 Zinc-finger double domain
301-323 Zinc finger, C2H2 type
301-321 C2H2-type zinc finger
301-323 C2H2-type zinc finger
316-340 Zinc-finger double domain
328-351 C2H2-type zinc finger
329-351 Zinc finger, C2H2 type
329-349 C2H2-type zinc finger
343-367 Zinc-finger double domain
356-379 C2H2-type zinc finger
357-379 Zinc finger, C2H2 type
357-379 C2H2-type zinc finger
371-395 Zinc-finger double domain
384-405 C2H2-type zinc finger
385-407 Zinc finger, C2H2 type
385-407 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 MEEEEMNDGSQMVRSQESLTFQDVAVDFTREEWDQLYPAQKNLYRDVMLENYRNLVALGY 60
61 QLCKPEVIAQLELEEEWVIERDSLLDTHPDGENRPEIKKSTTSQNISDENQTHEMIMERL 120
121 AGDSFWYSILGGLWDFDYHPEFNQENHKRYLGQVTLTHKKITQERSLECNKFAENCNLNS 180
181 NLMQQRIPSIKIPLNSDTQGNSIKHNSDLIYYQGNYVRETPYEYSECGKIFNQHILLTDH 240
241 IHTAEKPSECGKAFSHTSSLSQPQMLLTGEKPYKCDECGKRFSQRIHLIQHQRIHTGEKP 300
301 FICNGCGKAFRQHSSFTQHLRIHTGEKPYKCNQCGKAFSRITSLTEHHRLHTGEKPYECG 360
361 FCGKAFSQRTHLNQHERTHTGEKPYKCNECGKAFSQSAHLNQHRKIHTREKLCEYKCEQT 420
421 VRHSPSFSST*
Interface Residues: 198, 201, 204, 205, 207, 208, 211, 214, 233, 234, 235, 236, 239, 256, 258, 259, 262, 283, 284, 286, 287, 290, 294, 301, 312, 313, 314, 315, 317, 318, 320, 321, 322, 324, 339, 340, 341, 342, 343, 344, 345, 346, 367, 368, 369, 370, 371, 373, 374, 375, 395, 396, 397, 398, 399, 400, 401, 402, 403
3D-footprint Homologues: 8ssq_A, 8ssu_A, 5v3j_F, 5yel_A, 1tf6_A, 7w1m_H, 6jnm_A, 5kkq_D, 5ei9_F, 5kl3_A, 6a57_A, 2kmk_A, 5k5i_A, 6ml4_A, 6blw_A, 2gli_A, 7txc_E, 7ysf_A, 6e94_A, 2jpa_A, 1ubd_C, 1tf3_A, 7y3l_A, 7n5w_A, 2drp_D, 5k5l_F, 6u9q_A, 4x9j_A, 1f2i_J, 8gn3_A, 1g2f_F, 8h9h_G, 2lt7_A, 8cuc_F, 3uk3_C, 1llm_D, 2wbs_A, 4m9v_C, 7y3m_I, 5yj3_D
Binding Motifs: ZNF713_full WAGAArAAWGCCACGAA
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

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