Transcription Factor
| Accessions: | UP00367A (UniPROBE 20160601) |
| Names: | hlh-23, MXL-3 |
| Organisms: | Caenorhabditis elegans |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q18711 |
| Description: | MaX-Like: none available |
| Length: | 234 |
| Pfam Domains: | 47-98 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 SAIVEDMYLLSSSMKMEKQFRKRHHSDSSDDDSSSPKSASPSMDDDRRAHHNELERRRRD 60 61 HIKDHFTILKDAIPLLDGEKSSRALILKRAVEFIHVMQTKLSSQGKAIEDLTRKNELLEE 120 121 RLLERESSGSPSSSRLPALAVSSSQMQLTMPIIPQMQNIAQLSQYPQQANIIAQSTNPAQ 180 181 LDGLIALNNDAILALLGSFQSVSPSLLDSAPGTPPSGFYPCAFSPVDQQMAVKI |
| Interface Residues: | 48, 50, 51, 52, 54, 55, 58, 59, 83 |
| 3D-footprint Homologues: | 7z5k_B, 1an4_A, 7d8t_A, 4zpk_A, 7xi3_A, 5nj8_D, 7f2f_B, 5eyo_A, 5v0l_A, 1am9_A, 7rcu_E, 5gnj_I, 6g1l_A, 7ssa_L, 5i50_B |
| Binding Motifs: | UP00367A_1 yrdamCACGTGktymr |
| Binding Sites: | AACACGTG ACACGTGC ACACGTGG ACACGTGT ACCACGTG AGCACGTG ATCACGTG CACACGTG CACGTGAC CACGTGCA CACGTGCG CACGTGGA CACGTGGC CACGTGGG CACGTGTA CACGTGTC CCACGTGA CCACGTGC CCACGTGG GCACGTGC |
| Publications: | Grove C.A, De Masi F, Barrasa M.I, Newburger D.E, Alkema M.J, Bulyk M.L, Walhout A.J. A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 138:314-27 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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