Transcription Factor

Accessions: T134804_1.02 (CISBP 1.02)
Names: T134804_1.02;, VDR
Organisms: Petromyzon marinus
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:Nuclear receptor
Length: 406
Pfam Domains: 26-94 Zinc finger, C4 type (two domains)
204-379 Ligand-binding domain of nuclear hormone receptor
Sequence:
(in bold interface residues)
1 MMATQNMTVSTSNALEDDEEGGVPKVCGVCGDKATGYHFNAMTCEGCKGFFRRSMKRSAS 60
61 FTCPFEGKCNITKDNRRHCQACRLKRCRDIGMMKELIMTEEEVQRKKEIIMKRKLEDSAR 120
121 EVHTPQLLEEQERLIATLIEAHRKTYDASYSDFSQFRPPKRGDGSPECRNATNPFLMSLL 180
181 NSDMDELPKASASGAEAAAGDELSMLPHLADLVSYSIQKVIGFAKMIPGFKELCTEDQIS 240
241 LLKASAIEIIILRSNESFTMEDNSWTCGSNEFKYQIGDVMQAGHKLELLEPLVKFQVNMK 300
301 KLDLHEAEHVLLMAICLFSPDRPGVQDRCRVEEVQEHLTETLRAYIACRHPLSCKHMLYT 360
361 KMVEKLTELRSLNEEHSKQYLQISQDAVNKEDLPPLLLEVFGNPTA
Interface Residues: 35, 36, 38, 39, 45, 46, 48, 49, 52, 53, 77, 101, 106, 108
3D-footprint Homologues: 6fbq_A, 7wnh_D, 6l6q_B, 1lo1_A, 3g9m_B, 1a6y_A, 4oln_B, 7xvn_C, 4iqr_B, 2han_A, 1hcq_E, 8cef_H, 5krb_G, 2han_B, 1kb2_B, 2a66_A, 8hbm_B, 2nll_B, 1lat_A, 7xv6_B, 2ff0_A, 1dsz_A, 4umm_E, 3cbb_A, 5emc_A, 7prw_B, 5cbx_B, 3g6t_A, 1r4i_A, 5cbz_E, 4tnt_B, 5e69_A, 4hn5_B, 8rm6_A
Binding Motifs: M1493_1.02 ryGamCy
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.