Transcription Factor

						

			
Accessions: P52736 (JASPAR 2024)

			
Names: Zinc finger protein 133, Zinc finger protein 150, ZN133_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P52736
Length: 654
Pfam Domains:      2-41 KRAB box
  216-236 Zinc finger, C2H2 type
  216-234 C2H2-type zinc finger
  228-252 Zinc-finger double domain
  242-264 C2H2-type zinc finger
  242-264 Zinc finger, C2H2 type
  256-280 Zinc-finger double domain
  271-292 Zinc finger, C2H2 type
  272-292 C2H2-type zinc finger
  287-308 Zinc-finger double domain
  298-320 Zinc finger, C2H2 type
  298-320 C2H2-type zinc finger
  300-321 C2H2-type zinc finger
  312-336 Zinc-finger double domain
  326-348 Zinc finger, C2H2 type
  326-348 C2H2-type zinc finger
  342-364 Zinc-finger double domain
  355-376 Zinc finger, C2H2 type
  356-377 C2H2-type zinc finger
  356-376 C2H2-type zinc finger
  368-392 Zinc-finger double domain
  382-406 C2H2-type zinc finger
  382-404 Zinc finger, C2H2 type
  382-404 C2H2-type zinc finger
  397-420 Zinc-finger double domain
  410-432 C2H2-type zinc finger
  410-432 Zinc finger, C2H2 type
  410-432 C2H2-type zinc finger
  427-448 Zinc-finger double domain
  438-460 C2H2-type zinc finger
  438-448 C2H2-type zinc finger
  438-460 Zinc finger, C2H2 type
  452-476 Zinc-finger double domain
  467-488 Zinc finger, C2H2 type
  468-488 C2H2-type zinc finger
  468-489 C2H2-type zinc finger
  480-504 Zinc-finger double domain
  495-516 C2H2-type zinc finger
  495-516 Zinc finger, C2H2 type
  496-517 C2H2-type zinc finger
  508-533 Zinc-finger double domain
  522-544 Zinc finger, C2H2 type
  522-544 C2H2-type zinc finger
  522-545 C2H2-type zinc finger
  537-561 Zinc-finger double domain
  550-572 C2H2-type zinc finger
  552-573 C2H2-type zinc finger
  565-588 Zinc-finger double domain
  579-600 C2H2-type zinc finger
  592-616 Zinc-finger double domain
  606-627 Zinc finger, C2H2 type
  606-627 C2H2-type zinc finger
Sequence: 
(in bold interface residues)		   1 MAFRDVAVDFTQDEWRLLSPAQRTLYREVMLENYSNLVSLGISFSKPELITQLEQGKETW   60
  61 REEKKCSPATCPADPEPELYLDPFCPPGFSSQKFPMQHVLCNHPPWIFTCLCAEGNIQPG  120
 121 DPGPGDQEKQQQASEGRPWSDQAEGPEGEGAMPLFGRTKKRTLGAFSRPPQRQPVSSRNG  180
 181 LRGVELEASPAQSGNPEETDKLLKRIEVLGFGTVNCGECGLSFSKMTNLLSHQRIHSGEK  240
 241 PYVCGVCEKGFSLKKSLARHQKAHSGEKPIVCRECGRGFNRKSTLIIHERTHSGEKPYMC  300
 301 SECGRGFSQKSNLIIHQRTHSGEKPYVCRECGKGFSQKSAVVRHQRTHLEEKTIVCSDCG  360
 361 LGFSDRSNLISHQRTHSGEKPYACKECGRCFRQRTTLVNHQRTHSKEKPYVCGVCGHSFS  420
 421 QNSTLISHRRTHTGEKPYVCGVCGRGFSLKSHLNRHQNIHSGEKPIVCKDCGRGFSQQSN  480
 481 LIRHQRTHSGEKPMVCGECGRGFSQKSNLVAHQRTHSGERPYVCRECGRGFSHQAGLIRH  540
 541 KRKHSREKPYMCRQCGLGFGNKSALITHKRAHSEEKPCVCRECGQGFLQKSHLTLHQMTH  600
 601 TGEKPYVCKTCGRGFSLKSHLSRHRKTTSVHHRLPVQPDPEPCAGQPSDSLYSL
Interface Residues: 252, 253, 254, 255, 256, 259, 280, 281, 283, 284, 287, 308, 309, 311, 312, 315, 319, 337, 338, 339, 340, 343, 346, 347, 364, 365, 366, 367, 368, 370, 371, 392, 393, 394, 395, 396, 399, 410, 420, 421, 422, 423, 424, 426, 427, 428, 445, 447, 448, 449, 450, 451, 452, 453, 454, 455, 456, 457, 458, 461, 476, 477, 478, 479, 480, 482, 483, 504, 505, 506, 507, 508, 511, 533, 534, 535, 536, 538, 539, 542, 555, 561, 563, 564, 567, 571, 573, 587, 589, 591, 592, 595, 599, 616, 617, 618, 619, 620, 623
3D-footprint Homologues: 7n5w_A, 5k5i_A, 8ssq_A, 1f2i_J, 8h9h_G, 8cuc_F, 7y3l_A, 7txc_E, 2gli_A, 7y3m_I, 3uk3_C, 1tf3_A, 5k5l_F, 2wbs_A, 8ssu_A, 5yel_A, 5v3j_F, 7w1m_H, 1g2f_F, 6ml4_A, 6u9q_A, 4x9j_A, 5kkq_D, 2kmk_A, 1llm_D, 8gn3_A, 4m9v_C, 1ubd_C, 6blw_A, 5ei9_F, 7ysf_A, 2lt7_A, 6e94_A, 2jpa_A, 6jnm_A, 5kl3_A, 2drp_D, 6a57_A, 1tf6_A, 5yj3_D
Binding Motifs: UN0314.1 atGTATAATTGGwg
UN0314.2 GTATAATTGG
Binding Sites: UN0314.1.1
UN0314.1.10 / UN0314.1.8
UN0314.1.11 / UN0314.1.9
UN0314.1.10 / UN0314.1.12
UN0314.1.13
UN0314.1.11 / UN0314.1.14
UN0314.1.15
UN0314.1.12 / UN0314.1.16
UN0314.1.17
UN0314.1.13 / UN0314.1.18
UN0314.1.14 / UN0314.1.19
UN0314.1.2
UN0314.1.15 / UN0314.1.20
UN0314.1.3
UN0314.1.3 / UN0314.1.4
UN0314.1.5
UN0314.1.5 / UN0314.1.6
UN0314.1.6 / UN0314.1.7
UN0314.1.7 / UN0314.1.8
UN0314.1.9
UN0314.1.16
UN0314.1.17
UN0314.1.19
UN0314.1.20
UN0314.1.4
UN0314.2.1
UN0314.2.10 / UN0314.2.13 / UN0314.2.16 / UN0314.2.18 / UN0314.2.5 / UN0314.2.8
UN0314.2.11
UN0314.2.12
UN0314.2.14
UN0314.2.15
UN0314.2.17
UN0314.2.19
UN0314.2.2
UN0314.2.20
UN0314.2.3
UN0314.2.4
UN0314.2.6
UN0314.2.7
UN0314.2.9
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.