Transcription Factor
| Accessions: | TFE3 (HT-SELEX2 May2017) |
| Names: | ENSG00000068323, TFE3 |
| Organisms: | Homo sapiens |
| Libraries: | HT-SELEX2 May2017 1 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Notes: | TF family: bHLH experiment: HT-SELEX Hamming distance: 1 cycle: 4, TF family: bHLH experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 4 |
| Length: | 107 |
| Pfam Domains: | 18-71 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 KREISETEAKALLKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSSDPEMRWNKGTIL 60 61 KASVDYIRKLQKEQQRSKDLESRQRSLEQANRSLQLRIQELELQAQI |
| Interface Residues: | 19, 22, 23, 25, 26, 29, 30, 54, 56 |
| 3D-footprint Homologues: | 1a0a_B, 7ssa_L, 5nj8_D, 4h10_A, 7d8t_A, 5gnj_I, 7xi3_A, 5v0l_A, 4h10_B, 7f2f_B, 5i50_B, 8hov_A, 4zpk_A, 7rcu_E, 8ia3_B, 6g1l_A, 5eyo_A, 1am9_A, 8osl_P, 2ypa_B, 8osl_O, 1an4_A, 2ypa_A, 5nj8_C, 5v0l_B |
| Binding Motifs: | TFE3_2 yrCACGTGAys TFE3_methyl_1 rvCATGTGACs |
| Related annotations: | PaperBLAST |
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