Transcription Factor

Accessions: UP00273A (UniPROBE 20160601)
Names: J0922, Protein SIP4, Sip4, YJL089W
Organisms: Saccharomyces cerevisiae
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: P46954
Description: C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1...
Length: 131
Pfam Domains: 43-80 Fungal Zn(2)-Cys(6) binuclear cluster domain
Sequence:
(in bold interface residues)
1 AKRKYGRSYSLDDTDSCSNKVLIVPTGQSSSNAITDFSVRKAHACDRCRLKKIKCDGLKP 60
61 NCSNCAKIDFPCKTSDKLSRRGLPKGYTELLEKEVVRLTNMNASSSANANSNLPFINDTF 120
121 YCFDNYNTQSE
Interface Residues: 38, 39, 41, 49, 51, 52, 53, 54, 67, 68, 79, 81, 82
3D-footprint Homologues: 1f5e_P, 4umm_E, 1hwt_C, 1pyi_A, 2er8_C, 7uik_T, 3coq_A, 1d66_B, 1zme_D, 6gys_C
Binding Motifs: UP00273A_1 ysvyhwtTCCGGAawrhyyc
Binding Sites: AACTCCGG
ACTCATCG
ACTCCGGA
ACTCCGGC
ATCCGGAA
ATCTCATC
CCGATGAG
CCTCATCG
CCTCCGGA
CGATGACC
CGATGCCG
CTCATCCC
CTCATCGA
CTCATCGC
CTCATCTC
CTCCGGAG
GCGATGCC
TCCGGAAA
TTCCGGAA
GATCCGGA
Publications: *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.