Transcription Factor
| Accessions: | UP00273A (UniPROBE 20160601) |
| Names: | J0922, Protein SIP4, Sip4, YJL089W |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P46954 |
| Description: | C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1... |
| Length: | 131 |
| Pfam Domains: | 43-80 Fungal Zn(2)-Cys(6) binuclear cluster domain |
| Sequence: (in bold interface residues) | 1 AKRKYGRSYSLDDTDSCSNKVLIVPTGQSSSNAITDFSVRKAHACDRCRLKKIKCDGLKP 60 61 NCSNCAKIDFPCKTSDKLSRRGLPKGYTELLEKEVVRLTNMNASSSANANSNLPFINDTF 120 121 YCFDNYNTQSE |
| Interface Residues: | 38, 39, 41, 49, 51, 52, 53, 54, 67, 68, 79, 81, 82 |
| 3D-footprint Homologues: | 1f5e_P, 4umm_E, 2er8_C, 1hwt_C, 1pyi_A, 1d66_B, 1zme_D, 6gys_C, 7uik_T, 3coq_A |
| Binding Motifs: | UP00273A_1 ysvyhwtTCCGGAawrhyyc |
| Binding Sites: | AACTCCGG ACTCATCG ACTCCGGA ACTCCGGC ATCCGGAA ATCTCATC CCGATGAG CCTCATCG CCTCCGGA CGATGACC CGATGCCG CTCATCCC CTCATCGA CTCATCGC CTCATCTC CTCCGGAG GCGATGCC TCCGGAAA TTCCGGAA GATCCGGA |
| Publications: | *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed] |
| Related annotations: | PaperBLAST |
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