Transcription Factor
Accessions: | 1am9_A (3D-footprint 20231221) |
Names: | bHLHd1, Class D basic helix-loop-helix protein 1, SRBP1_HUMAN, SREBP-1, STEROL REGULATORY ELEMENT BINDING PROTEIN 1A, Sterol regulatory element-binding protein 1, Sterol regulatory element-binding transcription factor 1, Transcription factor SREBF1 |
Organisms: | Homo sapiens |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | P36956 |
Length: | 80 |
Pfam Domains: | 6-56 Helix-loop-helix DNA-binding domain |
Sequence: (in bold interface residues) | 1 QSRGEKRTAHNAIEKRYRSSINDKIIELKDLVVGTEAKLNKSAVLRKAIDYIRFLQHSNQ 60 61 KLKQENLSLRTAVHKSKSLK |
Interface Residues: | 7, 9, 10, 11, 13, 14, 17, 18, 39, 41, 74, 75, 76 |
3D-footprint Homologues: | 2ypa_A, 1an4_A, 7rcu_E, 5i50_B, 6g1l_A, 4h10_B, 7ssa_L, 7d8t_A, 4zpk_A, 7xi3_A, 5nj8_D, 7f2f_B, 5eyo_A, 1am9_A, 8osl_O, 5v0l_A, 4h10_A, 8osl_P, 5nj8_C, 2yvh_A |
Binding Motifs: | 1am9_A GgTGA 1am9_AB gTCaCcCCaC |
Binding Sites: | 1am9_G 1am9_F |
Publications: | Párraga A, Bellsolell L, Ferré-D'Amaré A.R, Burley S.K. Co-crystal structure of sterol regulatory element binding protein 1a at 2.3 A resolution. Structure (London, England : 1993) 6:661-72 (1998). [Pubmed] |
Related annotations: | PaperBLAST |
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