Transcription Factor
| Accessions: | 3zql_A (3D-footprint 20231221), 3zql_C (3D-footprint 20231221) |
| Names: | PUTATIVE REPRESSOR SIMREG2, Q9AMH9_STRAT, Sim16 |
| Organisms: | Streptomyces antibioticus |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | Q9AMH9 |
| Length: | 236 |
| Pfam Domains: | 26-70 Bacterial regulatory proteins, tetR family 83-233 Tetracyclin repressor, C-terminal all-alpha domain |
| Sequence: (in bold interface residues) | 1 VSIWMHPEPAGRRSARSHRTLSRDQIVRAAVKVADTEGVEAASMRRVAAELGAGTMSLYY 60 61 YVPTKEDLVELMVDEVIGETRLPDRPGPDWRAALTLAANEKRALWLRHPWLATAWRNGHP 120 121 VWGPNSLRQQEFVLGTLGVFDLQVDELLSLIGLYNGYVESFVRNEVGWLEEARRTKVDMR 180 181 EWMRRSGPYAQQLVDSGEYPMFARVLAETVAPHMGPDQRFRSGLERLLDSIGASLD |
| Interface Residues: | 16, 42, 43, 44, 45, 46, 49, 50, 54, 55, 56, 57, 59, 60, 164 |
| 3D-footprint Homologues: | 6wpa_A, 3ket_A, 5gpc_B, 6gy3_A, 5haw_A, 3zql_B, 5yej_B, 4gck_A, 5fmp_B, 1qpi_A, 4jl3_B, 7jnp_A, 4pxi_B, 7amn_A, 2yvh_A, 6en8_C, 5cl8_A |
| Binding Motifs: | 3zql_AB TCGTACGnCGTACAA 3zql_CD TTGTACGnCGTAcGA |
| Publications: | Le T.B, Schumacher M.A, Lawson D.M, Brennan R.G, Buttner M.J. The crystal structure of the TetR family transcriptional repressor SimR bound to DNA and the role of a flexible N-terminal extension in minor groove binding. Nucleic acids research 39:9433-47 (2011). [Pubmed] |
| Related annotations: | PaperBLAST |
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