Transcription Factor
| Accessions: | UP00508A (UniPROBE 20160601) |
| Names: | CG1447, D-Ptx1, Dmel\CG1447, Paired-type homeobox 1, Pituitary homeobox homolog Ptx1, Ptx1 |
| Organisms: | Drosophila melanogaster |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Description: | Paired-type homeobox 1 |
| Length: | 85 |
| Pfam Domains: | 12-68 Homeobox domain |
| Sequence: (in bold interface residues) | 1 EPKNDKKNKRQRRQRTHFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLTEARVRVWFK 60 61 NRRAKWRKRERNAMNAAVAAADFKS |
| Interface Residues: | 12, 13, 14, 15, 17, 53, 54, 56, 57, 60, 61, 64, 65, 68 |
| 3D-footprint Homologues: | 1ig7_A, 5zfz_A, 2h1k_B, 1puf_A, 3cmy_A, 6a8r_A, 3d1n_M, 1fjl_B, 1zq3_P, 4j19_B, 6m3d_C, 3lnq_A, 2lkx_A, 1jgg_B, 1nk2_P, 2ld5_A, 6es3_K, 1b72_A, 4xrs_G, 3l1p_A, 7q3o_C, 3a01_E, 5flv_I, 5zjt_E, 2hdd_A, 1mnm_C, 5hod_A, 3rkq_B, 2r5y_A, 1puf_B, 1au7_A, 2hos_A, 7psx_B, 1le8_B, 1k61_B, 5jlw_D, 1le8_A, 7xrc_C, 1e3o_C, 2xsd_C, 1o4x_A, 1du0_A, 4qtr_D, 6wig_A, 8g87_X, 4xrm_B, 4cyc_A |
| Binding Motifs: | UP00508A_1 wcctrrvGGGATTAAktrtcms |
| Binding Sites: | ACTAATCC AGGATTAA AGGGATTA ATAATCCC ATTAATCC CCGGATTA CGGATTAA CGGGATTA CTAATCCA CTAATCCC CTTAATCC GATAATCC GCTAATCC GGATTAAA GGATTAAC GGGATTAA GGGGATTA GTGGATTA TAATCCCA TGGATTAA |
| Publications: | Busser BW, Shokri L, Jaeger SA, Gisselbrecht SS, Singhania A, Berger MF, Zhou B, Bulyk ML, Michelson AM. Molecular mechanism underlying the regulatory specificity of a Drosophila homeodomain protein that specifies myoblast identity. Development 139:1164-74 (2012). [Pubmed] |
| Related annotations: | PaperBLAST |
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