Transcription Factor
| Accessions: | HOXA13 (HT-SELEX2 May2017) |
| Names: | ENSG00000106031, HOXA13 |
| Organisms: | Homo sapiens |
| Libraries: | HT-SELEX2 May2017 1 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Notes: | TF family: Homeodomain experiment: HT-SELEX Hamming distance: 1 cycle: 2, TF family: Homeodomain experiment: HT-SELEX Hamming distance: 1 cycle: 3, TF family: Homeodomain experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 2, TF family: Homeodomain experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 3 |
| Length: | 387 |
| Pfam Domains: | 78-132 Hox protein A13 N terminal 123-223 Hox protein A13 N terminal 322-378 Homeobox domain |
| Sequence: (in bold interface residues) | 1 TASVLLHPRWIEPTVMFLYDNGGGLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPHP 60 61 AAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAAA 120 121 AAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYPC 180 181 ARMGPHPNAIKSCAQPASAAAAAAFADKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGPYH 240 241 HHQPMPGYLDMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPHL 300 301 WKSTLPDVVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNL 360 361 SERQVTIWFQNRRVKEKKVINKLKTTS |
| Interface Residues: | 322, 323, 324, 325, 363, 364, 366, 367, 370, 371, 374, 375, 378 |
| 3D-footprint Homologues: | 1fjl_B, 2h1k_B, 5zfz_A, 1puf_A, 1ig7_A, 3cmy_A, 6a8r_A, 2lkx_A, 6m3d_C, 2p0j_A, 1jgg_B, 1nk2_P, 1zq3_P, 3lnq_A, 6es3_K, 7q3o_C, 2ld5_A, 4xrs_G, 1b72_A, 3rkq_B, 5flv_I, 3a01_E, 2hdd_A, 5zjt_E, 4cyc_A, 1puf_B, 5hod_A, 2hos_A, 2r5y_A, 7psx_B, 5jlw_D, 2xsd_C, 1le8_A, 7xrc_C, 6ryd_F, 1e3o_C, 1au7_A, 1o4x_A, 1mnm_C, 1du0_A, 4qtr_D, 1k61_B |
| Binding Motifs: | HOXA13_3 sCTCGTAAAay HOXA13_4 vCCMATAAAAc HOXA13_7 sCTCGTAAAah HOXA13_8 mCYaATAAAAm HOXA13_methyl_1 gCTCGTAAAah HOXA13_methyl_2 asYAATAAAAm HOXA13_methyl_5 sCTCGTAAAah HOXA13_methyl_6 rcCAATAAAmy |
| Related annotations: | PaperBLAST |
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