Transcription Factor

Accessions: T017943_1.02 (CISBP 1.02)
Names: NCU05970, T017943_1.02;
Organisms: Neurospora crassa
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:bHLH
Length: 497
Pfam Domains: 382-449 Helix-loop-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 MDPNTLRHLEYFSVPNHQTVNPVDQSYNLSGSTSTQSPTLWGTAPSLEANHSGMNSTATT 60
61 TMSLDSLSQTSPATAFTGMSSHPSMTRRPSMYGNHTGMPSSKSSRTREGHERKRTRLDSE 120
121 LSPFDEPDYWLQFDNDDNFDDLSEITEPPRQDHKGKGRAPQLSQQQEQQQQQQQQRRRST 180
181 AHSMATTAPTHRRTAGTLKSEDYMEDSALDNALSEDERAMSLNLAEQLSKIDTAPPQEVP 240
241 PREGLYSTPLSWERPQPGLRMDSLIGLNQQALNEAEQRRLIAIAMNPGPSMGGLGSNINL 300
301 NFGDMATGFNSGFGSSYASSSMGGGQMPRPVSPPRASTSSQSRPAPARPPHKHGSISEKS 360
361 SERMGSGDKHRKVEEKHKIGDRTAHNDIERKYRTNLKDKIAELREAVPALHTISEAGGVE 420
421 DDGSQNSRAPKVSKGTILTKATEYIHQLERRNKQITMEHRELSRKLQAFEQLLNHTAATA 480
481 YQMPAYSRTLFDPRGFC
Interface Residues: 384, 385, 386, 388, 389, 392, 393, 432
3D-footprint Homologues: 1an4_A, 5i50_B, 7rcu_E, 1am9_A, 6g1l_A, 7d8t_A, 5eyo_A, 7f2f_B
Binding Motifs: M0236_1.02 atcaCGTrmkaygt
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.