Transcription Factor

Accessions: 2ayb_A (3D-footprint 20231221), 2ayb_B (3D-footprint 20231221), 2ayg_A (3D-footprint 20231221), 2ayg_B (3D-footprint 20231221)
Names: Regulatory protein E2, VE2_HPV6A
Organisms: Human papillomavirus type 6a
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q84294
Length: 87
Pfam Domains: 5-83 E2 (early) protein, C terminal
Sequence:
(in bold interface residues)
1 SSATPIVQFQGESNCLKCFRYRLNDKHRHLFDLISSTWHWASPKAPHKHAIVTVTYHSEE 60
61 QRQQFLNVVKIPPTIRHKLGFMSMHLL
Interface Residues: 14, 17, 18, 20, 21, 22, 44, 46, 50, 56
3D-footprint Homologues: 1jj4_B, 2ayg_A, 2bop_A, 7rcf_A
Binding Motifs: 2ayb_AB CAACCGnnnnCGGTTG
2ayb_B CGGTTG
2ayg_A CGGTTG
2ayg_AB CAACCGnnnnCGGTTG
Binding Sites: 2ayb_C / 2ayb_D
2ayg_C / 2ayg_D
Publications: Hooley E, Fairweather V, Clarke A.R, Gaston K, Brady R.L. The recognition of local DNA conformation by the human papillomavirus type 6 E2 protein. Nucleic acids research 34:3897-908 (2006). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.