Transcription Factor

						

			
Accessions: Q4H2R8 (JASPAR 2024)

			
Names: Q4H2R8_CIOIN
Organisms: Ciona intestinalis
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q4H2R8
Length: 796
Pfam Domains:   179-243 Domain of unknown function (DUF1898)
  180-248 HMG (high mobility group) box
Sequence: 
(in bold interface residues)		   1 MTGLLHVVPPNNAGSGTLPYTIPSDEYSRSLTSFVDPYSSFSGYSPQRDYLESMGLLTRA   60
  61 VSGSSPESSKSVSTPSIFTAGLNSGLFYSQYSTVTSSTTSPYTSSSQWLSPQVTNAGHYQ  120
 121 QYACPYNLTNASQPSLAVNDQTSYLSSYPELYADTITNNTSVRSRKSTETAKAKKDEPRI  180
 181 RRPMNAFMCWAKTERKRMAAAFPDHHNAELSKMLGKKWKEMSNEDKRPYITEAEKLRMKH  240
 241 MQEHPDYKYRPRRKPKEPKSRRGKTTAADDKGVTGDHFGGSTNCGKTLNTKLGTTGKLVN  300
 301 GKSIYSANSLFSSDQAHVRRNHSNNNSRHGDKYGEGFSNSFSFYDSTASFPYASLESLFS  360
 361 NTPNSSSYQIKHKSPGERMKSLFDSCSSTSKCDINFDGQAYTNRANQSSLFNYNTTVSSP  420
 421 QIRNPIDFSCFTKYTAPSTNRYTDFTAVTTCQSTGLDPYATSGYSRSRQLSKDRFFSKHI  480
 481 KQTFMDTIHPSNCGFPTQSNLDQTYNAGNVDPVFDPINADLTSDNYYDTIPPFSCAGPRQ  540
 541 LPTYPAPGSTDTSYQVEHPDSSFVSDNLSFPSYKPADTKYFTPGLSATHDETKYNPMVAH  600
 601 NFTNMGYRSHENLASTSYTQSLKTEASPNAEMYDATTENCDWKKKGESEVYYQNGPPHYQ  660
 661 HSSQDELYETNSVQRYDKSPSTSRSLFMDSPTTSELHFESQNEAVRSSEPTEVDFVGSED  720
 721 QQRKMSVYYDPATTAENDAEFAKYEGKATAAQESVDIKTAPFGSEETNAVYSKESEATAS  780
 781 ISVTDSIGFEESNQQI
Interface Residues: 182, 185, 187, 188, 191, 195, 206, 207, 208, 211, 249, 251, 253, 263
3D-footprint Homologues: 7m5w_A, 1qrv_A, 3u2b_C, 2gzk_A, 4s2q_D, 1j5n_A, 2lef_A, 4y60_C, 1o4x_B, 3f27_D, 1hry_A
Binding Motifs: MA1918.1 awwwwyhATTGTthtttwww
MA1918.2 ATTGTt
			
Publications: Chen WC, Pauls S, Bacha J, Elgar G, Loose M, Shimeld SM. Dissection of a Ciona regulatory element reveals complexity of cross-species enhancer activity. Dev Biol 390:261-72 (2014). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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