Transcription Factor
| Accessions: | Q9W2Q1 (JASPAR 2024) |
| Names: | DRx, DRx1, Retinal homeobox protein Rx, RX_DROME |
| Organisms: | Drosophila melanogaster |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q9W2Q1 |
| Length: | 873 |
| Pfam Domains: | 529-585 Homeobox domain 844-862 OAR domain |
| Sequence: (in bold interface residues) | 1 MSGSGGVANSSSTAAANNTAATFQHIFEQLVQQGGGNHKLPPKQLEQLRHLLGNVRDAKN 60 61 LQMIVEKFKNLEQFHEHYAAHLANNNTVISTEDSNDLVKDNARKYGSGGQTLTPRHTIDA 120 121 ILGLKNRNGAANGSGRNPETVSDGSVDPSLGDDDATDLRCGMTLTQLRSMDNHMASMLQQ 180 181 HAKNGGALPYGPPTPPGGQQPQVPNATPLHHGQQMGGQAGHATHAGHGHPTHHGHAPFGY 240 241 HNAFGFGQGGHGYGHPEEAAGNYLNSMHQMVEANQLQTGANGANPPPAPLPPSSFGSHQQ 300 301 HLAALAAQAQEQQNQHSKYAKSSPTGAGPPPPPGAYFMESQTAPVAPSQINYDERSMSSA 360 361 SDLEEDDDDAAKLQLDVTSPPTPSPRGQLAAKRKSAGVFCDDNEPKLANGQLPGGNYGIR 420 421 PRSMEEVHHQQQSHHHQQQQQQQQQQQQLQQQQGFQHDFRNSGNGNPNGNSNSGDHGERL 480 481 NADSDSLVNGSCASSEDLNQTNSSEQGEKITSGSDDEGQDDNCAKKKHRRNRTTFTTYQL 540 541 HELERAFEKSHYPDVYSREELAMKVNLPEVRVQVWFQNRRAKWRRQEKSESLRLGLTHFT 600 601 QLPHRLGCGASGLPVDPWLSPPLLSALPGFLSHPQTVYPSYLTPPLSLAPGNLTMSSLAA 660 661 MGHHHAHNGPPPPHVGHGGHGQPQPPPPPPPHGVPHPHGSHHVVPLSHLSPHLSRMSPHA 720 721 TSLGSPHHGVTPLGTPLHSSLPPSSTATTVAVSSSQSSSSSASLECSGPDVCMSPQNLSI 780 781 GNADSNGDGRDLSSDLDAGSTSSNPGSSLDKCAASANIELLDVGRDSPPPPPTPTGKGSS 840 841 TPPTDMRSNSIATLRIKAKEHLDNLNKGMVSIV |
| Interface Residues: | 529, 530, 531, 532, 570, 571, 573, 574, 577, 578, 581, 582, 585 |
| 3D-footprint Homologues: | 1puf_B, 1fjl_B, 3d1n_M, 5zfz_A, 1ig7_A, 2h1k_B, 1puf_A, 6a8r_A, 3cmy_A, 1nk2_P, 1zq3_P, 6m3d_C, 1jgg_B, 3lnq_A, 2lkx_A, 6es3_K, 2ld5_A, 7q3o_C, 4xrs_G, 2hos_A, 1b72_A, 4cyc_A, 5flv_I, 3l1p_A, 5zjt_E, 4j19_B, 3a01_E, 7psx_B, 5hod_A, 2hdd_A, 1au7_A, 5jlw_D, 3rkq_B, 2r5y_A, 7xrc_C, 2xsd_C, 1e3o_C, 1le8_A, 1o4x_A, 8g87_X, 1du0_A, 4qtr_D |
| Binding Motifs: | MA0202.1 yTAATTr |
| Binding Sites: | MA0202.1.18 MA0202.1.2 / MA0202.1.3 MA0202.1.6 MA0202.1.19 MA0202.1.16 MA0202.1.12 MA0202.1.7 MA0202.1.1 MA0202.1.10 MA0202.1.11 MA0202.1.13 MA0202.1.14 MA0202.1.15 MA0202.1.17 MA0202.1.20 MA0202.1.4 MA0202.1.5 MA0202.1.8 MA0202.1.9 |
| Publications: | Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.