Transcription Factor

Accessions: 5vxn_A (3D-footprint 20231221)
Names: Capsular synthesis regulator component B, RCSB_ECOLI, Transcriptional regulatory protein RcsB
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 201
Pfam Domains: 5-119 Response regulator receiver domain
135-185 Sigma-70, region 4
141-196 Bacterial regulatory proteins, luxR family
Sequence:
(in bold interface residues)
1 NNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMPG 60
61 DKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKALA 120
121 ALQKGKKFTPESVSRLLEKIKRLSPKESEVLRLFAEGFLVTEIAKKLNRSIKTISSQKKS 180
181 AMMKLGVENDIALLNYLSSVT
Interface Residues: 90, 91, 92, 94, 95, 116, 170, 171, 172, 173, 175, 176, 177, 179
3D-footprint Homologues: 3zpl_B, 7ve5_B, 5w43_B, 4wuh_B, 1je8_F, 1zlk_A, 6ide_A
Binding Motifs: 5vxn_AB TAAGAnnnnTCCTA
Publications: Filippova EV, Zemaitaitis B, Aung T, Wolfe AJ, Anderson WF. Structural Basis for DNA Recognition by the Two-Component Response Regulator RcsB. MBio : (2018). [Pubmed]
Related annotations: PaperBLAST

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