Transcription Factor

Accessions: 1k61_B (3D-footprint 20231221)
Names: Alpha-2 repressor, MATalpha2 protein, Mating-type protein alpha-2, Mating-type protein ALPHA2, MTAL2_YEAST
Organisms: Saccharomyces cerevisiae, Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P0CY08
Length: 59
Pfam Domains: 4-57 Homeobox domain
16-54 Homeobox KN domain
Sequence:
(in bold interface residues)
1 RGHRFTKENVRILESWFAKNIENPYLDTKGLENLMKNTSLSRIQIKNWVSNRRRKEKTI
Interface Residues: 1, 3, 4, 43, 44, 46, 47, 50, 51, 54, 55, 58
3D-footprint Homologues: 1mnm_C, 1k61_B, 1le8_B, 4j19_B, 2ld5_A, 5jlw_D, 2xsd_C, 7q3o_C, 1e3o_C, 7xrc_C, 1ig7_A, 7psx_B, 4xrs_G, 1nk2_P, 1du0_A, 6es3_K, 3rkq_B, 5flv_I, 3a01_E, 1puf_B, 6fqp_B, 3cmy_A, 1zq3_P, 6fqq_E, 4xrm_B, 2lkx_A, 8g87_X, 1b72_A, 5zjt_E, 3d1n_M, 2hdd_A, 1jgg_B, 2hos_A
Binding Motifs: 1k61_ABCD GCTTGTAAAnGAATTACA
1k61_B TGTAntTnnnnnrC
Binding Sites: 1k61_E
1k61_F
Publications: Aishima J, Gitti R.K, Noah J.E, Gan H.H, Schlick T, Wolberger C. A Hoogsteen base pair embedded in undistorted B-DNA. Nucleic acids research 30:5244-52 (2002). [Pubmed]
Related annotations: PaperBLAST

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