Transcription Factor

Accessions: UP00100A (UniPROBE 20160601)
Names: AA410133, GATA binding protein 6, GATA-6, GATA-binding factor 6, Gata6, Transcription factor GATA-6
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q61169
Description: GATA binding protein 6
Length: 135
Pfam Domains: 22-55 GATA zinc finger
76-109 GATA zinc finger
Sequence:
(in bold interface residues)
1 PLPVPRGPSTDLLEDLSESRECVNCGSIQTPLWRRDGTGHYLCNACGLYSKMNGLSRPLI 60
61 KPQKRVPSSRRLGLSCANCHTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMKKEGI 120
121 QTRKRKPKNINKSKA
Interface Residues: 31, 32, 34, 44, 48, 85, 86, 88, 98, 102, 103, 106, 123, 125, 126
3D-footprint Homologues: 3vd6_C, 4hc9_A, 3dfx_B, 1gat_A, 4gat_A
Binding Motifs: UP00100A_1 wawmkwGATAAGarttr
UP00100A_2 gsgrCGATATCGsmgyd
Binding Sites: AGATAACA
AAGATAAG
ACTGATAA
AGATAACG
AGATAAGA
AGATAAGC
CAGATAAG
CCTTATCA
CGAGATAA
CGATAAGA
CTCTTATC
CTGATAAC
CTGATAAG
CTTATCAA
CTTATCTA
CTTATCTC
GATAAGAA
GCTTATCA
TCTTATCA
TCAGATAA
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

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