Transcription Factor
| Accessions: | ZNF467 (humanC2H2ZF-ChIP Feb2015), Q7Z7K2 (JASPAR 2024) |
| Names: | ENSG00000181444, Q7Z7K2, ZNF467, ZN467_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | humanC2H2ZF-ChIP Feb2015 1, JASPAR 2024 2 1 Najafabadi HS, Mnaimneh S, Schmitges FW, Garton M, Lam KN, Yang A, Albu M, Weirauch MT, Radovani E, Kim PM, Greenblatt J, Frey BJ, Hughes TR. C2H2 zinc finger proteins greatly expand the human regulatory lexicon. Nat Biotechnol 33:555-62 (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | TF family: C2H2 experiment: ChIP-seq/MEME/B1H-RC |
| Length: | 595 |
| Pfam Domains: | 160-184 C2H2-type zinc finger 175-199 Zinc-finger double domain 189-210 C2H2-type zinc finger 189-210 Zinc finger, C2H2 type 205-226 Zinc-finger double domain 216-238 Zinc finger, C2H2 type 216-238 C2H2-type zinc finger 216-238 C2H2-type zinc finger 230-254 Zinc-finger double domain 244-266 Zinc finger, C2H2 type 244-266 C2H2-type zinc finger 244-266 C2H2-type zinc finger 261-282 Zinc-finger double domain 272-292 C2H2-type zinc finger 272-294 Zinc finger, C2H2 type 272-294 C2H2-type zinc finger 286-311 Zinc-finger double domain 300-322 C2H2-type zinc finger 300-322 Zinc finger, C2H2 type 300-322 C2H2-type zinc finger 355-377 Zinc finger, C2H2 type 355-376 C2H2-type zinc finger 431-446 C2H2-type zinc finger 431-449 Zinc finger, C2H2 type 432-449 C2H2-type zinc finger 445-469 Zinc-finger double domain 459-481 C2H2-type zinc finger 459-482 C2H2-type zinc finger 473-498 Zinc-finger double domain 487-509 C2H2-type zinc finger 487-509 C2H2-type zinc finger 487-509 Zinc finger, C2H2 type 502-526 Zinc-finger double domain 515-537 C2H2-type zinc finger 515-534 C2H2-type zinc finger 515-537 Zinc finger, C2H2 type 529-554 Zinc-finger double domain 543-565 Zinc finger, C2H2 type 543-565 C2H2-type zinc finger 543-554 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MRETLEALSSLGFSVGQPEMAPQSEPREGSHNAQEQMSSSREERALGVCSGHEAPTPEEG 60 61 AHTEQAEAPCRGQACSAQKAQPVGTCPGEEWMIRKVKVEDEDQEAEEEVEWPQHLSLLPS 120 121 PFPAPDLGHLAAAYKLEPGAPGALSGLALSGWGPMPEKPYGCGECERRFRDQLTLRLHQR 180 181 LHRGEGPCACPDCGRSFTQRAHMLLHQRSHRGERPFPCSECDKRFSKKAHLTRHLRTHTG 240 241 ERPYPCAECGKRFSQKIHLGSHQKTHTGERPFPCTECEKRFRKKTHLIRHQRIHTGERPY 300 301 QCAQCARSFTHKQHLVRHQRVHQTAGPARPSPDSSASPHSTAPSPTPSFPGPKPFACSDC 360 361 GLSFGWKKNLATHQCLHRSEGRPFGCDECALGATVDAPAAKPLASAPGGPGCGPGSDPVV 420 421 PQRAPSGERSFFCPDCGRGFSHGQHLARHPRVHTGERPFACTQCDRRFGSRPNLVAHSRA 480 481 HSGARPFACAQCGRRFSRKSHLGRHQAVHTGSRPHACAVCARSFSSKTNLVRHQAIHTGS 540 541 RPFSCPQCGKSFSRKTHLVRHQLIHGEAAHAAPDAALAAPAWSAPPEVAPPPLFF |
| Interface Residues: | 143, 145, 146, 149, 171, 172, 173, 174, 177, 198, 199, 201, 202, 204, 205, 207, 208, 211, 226, 227, 228, 229, 230, 233, 254, 255, 256, 257, 258, 260, 261, 264, 265, 282, 283, 284, 285, 286, 288, 289, 290, 293, 309, 311, 312, 313, 314, 315, 317, 318, 364, 365, 366, 367, 368, 395, 398, 401, 405, 416, 417, 420, 438, 439, 440, 441, 442, 444, 445, 447, 448, 459, 470, 471, 472, 473, 476, 482, 496, 497, 498, 499, 500, 501, 504, 508, 525, 526, 527, 528, 529, 531, 532, 554, 556, 557, 560 |
| 3D-footprint Homologues: | 5und_A, 8ssq_A, 8ssu_A, 5k5i_A, 1ubd_C, 1tf3_A, 6jnm_A, 7txc_E, 2gli_A, 1tf6_A, 5kkq_D, 6u9q_A, 6wmi_A, 2i13_A, 6a57_A, 5yel_A, 2jpa_A, 7n5w_A, 3uk3_C, 1g2f_F, 5k5l_F, 7w1m_H, 4x9j_A, 1llm_D, 6blw_A, 2wbs_A, 5ei9_F, 5kl3_A, 1f2i_J, 7eyi_G, 7ysf_A, 6e94_A, 7y3m_I, 1mey_C, 8h9h_G, 2lt7_A, 4m9v_C, 7r8i_A, 5v3j_F, 7y3l_A, 2kmk_A, 6ml4_A, 8cuc_F, 8gn3_A, 2drp_D, 5yj3_D |
| Binding Motifs: | ZNF467_ChIP gGGGAGGGg UN0326.1 cybCCCCTCCCCcyc UN0326.2 CCCCTCCCCc |
| Binding Sites: | UN0326.2.10 UN0326.1.1 UN0326.1.10 / UN0326.1.9 UN0326.1.11 UN0326.1.10 / UN0326.1.12 UN0326.1.11 / UN0326.1.13 UN0326.1.14 UN0326.1.15 UN0326.1.16 UN0326.1.12 / UN0326.1.17 UN0326.1.13 / UN0326.1.18 UN0326.1.14 / UN0326.1.19 UN0326.1.2 UN0326.1.15 / UN0326.1.20 UN0326.1.3 UN0326.1.4 UN0326.1.5 UN0326.1.6 UN0326.1.7 UN0326.1.8 UN0326.1.9 UN0326.2.17 UN0326.2.6 UN0326.2.3 UN0326.1.16 UN0326.1.17 UN0326.1.18 UN0326.1.19 UN0326.1.20 UN0326.2.1 UN0326.2.16 UN0326.2.11 UN0326.2.12 UN0326.2.13 / UN0326.2.20 UN0326.2.14 UN0326.2.15 UN0326.2.18 / UN0326.2.8 UN0326.2.19 UN0326.2.2 UN0326.2.4 UN0326.2.5 UN0326.2.7 UN0326.2.9 |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.