Transcription Factor

						

			
Accessions: 6cnc_R (3D-footprint 20231221)

			
Names: TATA sequence-binding protein, TATA-binding factor, TATA-box factor, TBP_YEAST, Transcription factor D, Transcription factor IIIB 70 kDa subunit,TATA-box-binding protein,Transcription factor IIIB 70 kDa subunit, Transcription initiation factor TFIID TBP subunit
Organisms: Saccharomyces cerevisiae, Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 522
Pfam Domains:      3-41 TFIIB zinc-binding
   59-127 Transcription factor TFIIB repeat
  152-225 Transcription factor TFIIB repeat
  272-354 Transcription factor TFIID (or TATA-binding protein, TBP)
  359-444 Transcription factor TFIID (or TATA-binding protein, TBP)
  479-521 Brf1-like TBP-binding domain
Sequence: 
(in bold interface residues)		   1 MPVCKNCHGTEFERDLSNANNDLVCKACGVVSEDNPIVSEVALESREATLNNARRKLRAV   60
  61 SYALHIPEYITDAAFQWYKLALANNFVQGRRSQNVIASCLYVACRKEKTHHMLIDFSSRL  120
 121 QVSVYSIGATFLKMVKKLHITELPLADPSLFIQHFAEKLDLADKKIKVVKDAVKLAQRMS  180
 181 KDWMFEGRRPAGIAGACILLACRMNNLRRTHTEIVAVSHVAEETLQQRLNEFKNTKAAKL  240
 241 SVQKFRENDVEDGEARPPSFVKNRKKESGIVPTLQNIVATVTLGCRLDLKTVALHARNAE  300
 301 YNPKRFAAVIMRIREPKTTALIFASGKMVVTGAKSEDDSKLASRKYARIIQKIGFAAKFT  360
 361 DFKIQNIVGSCDVKFPIRLEGLAFSHGTFSSYEPELFPGLIYRMVKPKIVLLIFVSGKIV  420
 421 LTGAKQREEIYQAFEAIYPVLSEFRKMSGSPRNLHLLPTTDTYLSKVSDDPDNLEDVDDE  480
 481 ELNAHLLNEEASKLKERIWIGLNADFLLEQESKRLKQEADIA
Interface Residues: 13, 14, 16, 26, 30, 45, 88, 91, 223, 226, 276, 278, 306, 307, 321, 323, 329, 331, 365, 366, 368, 397, 398, 412, 414, 420, 422
3D-footprint Homologues: 3dfx_B, 6cnb_R, 6eu0_Z, 8ity_V, 1c9b_M, 1ytb_A, 5n9g_G, 7z7n_D, 5oqj_O, 1cdw_A, 4wzs_D, 1qna_B, 5iy6_P, 1ais_A
Binding Motifs: 6cnc_R AnnnnnnnnnnnnnACTAATAnnTGT
Binding Sites: 6cnc_X
6cnc_Y
			
Publications: Han Y, Yan C, Fishbain S, Ivanov I, He Y. Structural visualization of RNA polymerase III transcription machineries. Cell Discov : (2018). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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