Transcription Factor

Accessions: 1nkp_B (3D-footprint 20231221)
Names: bHLHd4, Class D basic helix-loop-helix protein 4, Max protein, MAX_HUMAN, Myc-associated factor X, Protein max
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P61244
Length: 83
Pfam Domains: 2-52 Helix-loop-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 DKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQ 60
61 QDIDDLKRQNALLEQQVRALGGC
Interface Residues: 3, 5, 6, 7, 9, 10, 13, 14, 18, 38
3D-footprint Homologues: 1a0a_B, 7z5k_B, 1an4_A, 7f2f_B, 5eyo_A, 7xq5_A, 5v0l_A, 4h10_A, 7rcu_E, 5gnj_I, 6g1l_A, 4h10_B, 7ssa_L, 5i50_B, 1am9_A, 8osl_O, 7d8t_A, 4zpk_A, 7xi3_A, 5nj8_D
Binding Motifs: 1nkp_AB gCACGTGCT
Binding Sites: 1nkp_F / 1nkp_G
Publications: Nair S.K, Burley S.K. X-ray structures of Myc-Max and Mad-Max recognizing DNA. Molecular bases of regulation by proto-oncogenic transcription factors. Cell 112:193-205 (2003). [Pubmed]
Related annotations: PaperBLAST

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