Transcription Factor

Accessions: UP00393A (UniPROBE 20160601), UP00478B (UniPROBE 20160601)
Names: NONE, PFF0200c, PFF0200c_DLD
Organisms: Plasmodium falciparum
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Description: putative Plasmodium falciparum transcription factor, tandem double AP2 domain
Length: 136
Pfam Domains: 88-130 AP2 domain
Sequence:
(in bold interface residues)
1 IGSQEPVILIDKIERCLVVEWYENNIRREQRISYKKYGNDKAKLRAKELIEKLKSGITFE 60
61 QLYPDKGPPIVRVFENVGVYNVSLIRDRIEREWRVEWLENGVPMKARWSCKKVGNDEAQK 120
121 RADTFAQSMIKGIFNP
Interface Residues: 119, 122, 123
3D-footprint Homologues: 7lw8_A
Binding Motifs: UP00393A_1 gArGGGTGCACCyh
UP00478B_1 cwtrasAwrGGTGCACyswwstt
Binding Sites: AGGGTGCA
AGGTGCAC
AGTGCACC
AGTGCACT
ATGCACCC
ATGGTGCA
CGGTGCAC
CGTGCACC
GAGGTGCA
GAGTGCAC
GCGCACCC
GGGGTGCA
GGGTGCAA
GGGTGCAC
GGTGCACA
GGTGCACC
GTGCACAA
GTGCACCA
GTGGTGCA
TGCACCCA
CAGTGCAC
CGCACCCC
GATGCACC
GGTGCATA
GTGCACTA
Publications: De Silva EK, Gehrke AR, Olszewki K, Leon I, Chahal JS, Bulyk ML, Llinas M. Specific DNA-binding by Apicomplexan AP2 transcription factors. Proc. Natl. Acad. Sci. USA. June 17, 2008; vol. 105, no. 24, 8393-8398 [Pubmed]

Campbell TL, De Silva EK, Olszewski KL, Elemento O, Llinás M. Identification and genome-wide prediction of DNA binding specificities for the ApiAP2 family of regulators from the malaria parasite. PLoS Pathog : (2010). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.