Transcription Factor

Accessions: 1io4_B (3D-footprint 20231221)
Names: C/EBP beta, CAAT/ENHANCER BINDING PROTEIN BETA, CCAAT/enhancer-binding protein beta, CEBPB_HUMAN, LAP, LIP, Liver activator protein, Liver-enriched inhibitory protein, Nuclear factor NF-IL6, TCF-5, Transcription factor 5
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P17676
Length: 70
Pfam Domains: 6-59 Basic region leucine zipper
7-65 bZIP transcription factor
Sequence:
(in bold interface residues)
1 KTVDKHSDEYKIRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKKVEQLSREL 60
61 STLRNLFKQL
Interface Residues: 14, 17, 18, 20, 21, 24, 25
3D-footprint Homologues: 1nwq_C, 6mg1_B, 2c9l_Z, 2dgc_A
Binding Motifs: 1io4_B tcnaAa
1io4_ABC TTTCCAAAnnnTGTGGT
Binding Sites: 1io4_E
1io4_F
Publications: Tahirov T.H, Inoue-Bungo T, Morii H, Fujikawa A, Sasaki M, Kimura K, Shiina M, Sato K, Kumasaka T, Yamamoto M, Ishii S, Ogata K. Structural analyses of DNA recognition by the AML1/Runx-1 Runt domain and its allosteric control by CBFbeta. Cell 104:755-67 (2001). [Pubmed]
Related annotations: PaperBLAST

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