Transcription Factor
| Accessions: | 3iv5_B (3D-footprint 20231221), 3jr9_B (3D-footprint 20231221), 3jra_B (3D-footprint 20231221), 3jrb_B (3D-footprint 20231221), 3jrc_B (3D-footprint 20231221), 3jrd_B (3D-footprint 20231221), 3jre_B (3D-footprint 20231221), 3jrf_B (3D-footprint 20231221), 3jrg_B (3D-footprint 20231221), 3jrh_B (3D-footprint 20231221), 3jri_B (3D-footprint 20231221), 4ihv_B (3D-footprint 20231221), 4ihw_B (3D-footprint 20231221), 4ihx_B (3D-footprint 20231221), 4ihy_B (3D-footprint 20231221), 5ds9_B (3D-footprint 20231221), 5dtd_B (3D-footprint 20231221), 5e3l_B (3D-footprint 20231221), 5e3m_B (3D-footprint 20231221), 5e3n_B (3D-footprint 20231221), 5e3o_B (3D-footprint 20231221) |
| Names: | DNA-binding protein fis, Factor-for-inversion stimulation protein, FIS_ECOLI, Hin recombinational enhancer-binding protein |
| Organisms: | Escherichia coli, strain K12 |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | P0A6R3 |
| Length: | 98 |
| Pfam Domains: | 55-95 Bacterial regulatory protein, Fis family |
| Sequence: (in bold interface residues) | 1 MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ 60 61 PLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN |
| Interface Residues: | 84, 85, 87, 89, 90 |
| 3D-footprint Homologues: | 5ds9_A |
| Binding Motifs: | 4ihv_B canaCA 3iv5_AB TGTnTGnnnnnTGnGCA 3iv5_B CanACA 3jr9_AB TGTnGAnnnnnTCnGCA 3jr9_B TanaCA 3jra_AB TAgntAnnnnnTGncCA 3jra_B TgncCA 3jrb_AB TGTnTGnnnnTTGnGCA 3jrb_B TGTnTG 3jrc_AB TGnnTgnnnnntCngCA 3jrc_B CAnaCA 3jrd_AB TGCnCAnnnnnCAnACA 3jrd_B canACA 3jre_AB TGTntGnnnnnTgnGCA 3jre_B CanACA 3jrf_AB TGTnAGnnnnnTCnGCA 3jrf_B CAnACA 3jrg_AB TGTnGGnnnnnTCnGCA 3jrg_B cnaCA 3jrh_AB TGTnAcnnnnngGnGCA 3jrh_B GAnACA 3jri_AB TGnnannnnnnncnGCA 3jri_B cnaCA 4ihv_AB TGtnTGnnnnnTrnnCA 4ihw_AB TGtnngnnnnnTrnnCA 4ihw_B CanACA 4ihx_AB TGCnCAnnnnCAAAC 4ihx_B TGTTT 4ihy_AB TGCnyAnnnnnCrnaCA 4ihy_B CAnACA 5ds9_AB AGCnCAnnnnnCAnACT 5dtd_AB CGTnnGnnnnnTCngCG 5e3l_AB GGCnCAnnnnnCAnACC 5e3l_B CAnACC 5e3m_AB AGCnCGnnnnnCAnACT 5e3n_AB TGCngAnnnnnCcnACA 5e3n_B ccnACA 5e3o_AB TGGnGGnnnnnTcnCCA 5e3o_B CCnCCA |
| Binding Sites: | 3iv5_C 3iv5_D 3jr9_C 3jr9_D 3jra_C 3jra_D 3jrb_C 3jrb_D 3jrc_C 3jrc_D 3jrd_C 3jrd_D 3jre_C 3jre_D 3jrf_C 3jrf_D 3jrg_C 3jrg_D 3jrh_C 3jrh_D 3jri_C 3jri_D 4ihv_C 4ihv_D 4ihw_C 4ihw_D 4ihx_C 4ihx_D 4ihy_C 4ihy_D 5dtd_C 5dtd_D 5e3l_C 5e3l_D 5e3m_C 5e3m_D 5e3n_C 5e3n_D 5e3o_C 5e3o_D 5ds9_C 5ds9_D |
| Publications: | Stella S, Cascio D, Johnson R.C. The shape of the DNA minor groove directs binding by the DNA-bending protein Fis. Genes & development 24:814-26 (2010). [Pubmed] Hancock S.P, Ghane T, Cascio D, Rohs R, Di Felice R, Johnson R.C. Control of DNA minor groove width and Fis protein binding by the purine 2-amino group. Nucleic acids research 41:6750-60 (2013). [Pubmed] Hancock SP, Stella S, Cascio D, Johnson RC. DNA Sequence Determinants Controlling Affinity, Stability and Shape of DNA Complexes Bound by the Nucleoid Protein Fis. PLoS One : (2016). [Pubmed] |
| Related annotations: | PaperBLAST |
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