Transcription Factor

Accessions: 3fhz_D (3D-footprint 20231221)
Names: Arginine repressor, ARGR_MYCTU
Organisms: Mycobacterium tuberculosis, strain ATCC 25618 / H37Rv
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P9WPY8
Length: 166
Pfam Domains: 12-81 Arginine repressor, DNA binding domain
97-164 Arginine repressor, C-terminal domain
Sequence:
(in bold interface residues)
1 KAAPVAGPEVAANRAGRQARIVAILSSAQVRSQNELAALLAAEGIEVTQATLSRDLEELG 60
61 AVKLRGADGGTGIYVVPEDGSPVRGVSGGTDRMARLLGELLVSTDDSGNLAVLRTPPGAA 120
121 HYLASAIDRAALPQVVGTIAGDDTILVVAREPTTGAQLAGMFENLR
Interface Residues: 48, 49, 50, 51, 53, 54
3D-footprint Homologues: 2p5l_D, 3lap_B, 4u7b_B
Binding Motifs: 3fhz_AD TGCATAnngATTMA
Binding Sites: 3fhz_K
3fhz_L
Publications: Cherney L.T, Cherney M.M, Garen C.R, James M.N. The structure of the arginine repressor from Mycobacterium tuberculosis bound with its DNA operator and Co-repressor, L-arginine. Journal of molecular biology 388:85-97 (2009). [Pubmed]
Related annotations: PaperBLAST

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