Transcription Factor

						

			
Accessions: 6oeo_N (3D-footprint 20231221)

			
Names: High mobility group protein 1, High mobility group protein B1, HMG-1, HMGB1_HUMAN
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P09429
Length: 54
Pfam Domains:      1-54 HMG (high mobility group) box
     1-54 Domain of unknown function (DUF1898)
Sequence: 
(in bold interface residues)		   1 AFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTADDKQPYEKKAAKLKEKY
Interface Residues: 2, 3, 6, 10, 21, 22, 23, 26
3D-footprint Homologues: 4y60_C, 1o4x_B, 3tq6_B, 1ckt_A, 6jrp_D, 1qrv_A, 3u2b_C, 1hry_A, 7m5w_A, 2gzk_A, 4s2q_D, 1j5n_A, 3tmm_A
Binding Motifs: 6oeo_ABN GnnnnnnnnnnnTGTG
Binding Sites: 6oeo_F
6oeo_I
			
Publications: Chen X, Cui Y, Best RB, Wang H, Zhou ZH, Yang W, Gellert M. Cutting antiparallel DNA strands in a single active site. Nat Struct Mol Biol 27:119-126 (2020). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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