Transcription Factor

Accessions: 6ml4_A (3D-footprint 20231221), 6ml6_A (3D-footprint 20231221), 6ml7_A (3D-footprint 20231221)
Names: Bone morphogenetic protein-induced factor 1, Brain-specific protein 1, ZBT24_MOUSE, Zinc finger and BTB domain-containing protein 24, Zinc finger protein 450
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q80X44
Length: 143
Pfam Domains: 5-15 C2H2-type zinc finger
5-27 Zinc finger, C2H2 type
5-27 C2H2-type zinc finger
34-54 Zinc-finger of C2H2 type
34-55 C2H2-type zinc finger
34-55 C2H2-type zinc finger
48-71 Zinc-finger double domain
60-84 C2H2-type zinc finger
61-83 C2H2-type zinc finger
61-83 Zinc-finger of C2H2 type
61-83 Zinc finger, C2H2 type
75-99 Zinc-finger double domain
89-111 C2H2-type zinc finger
89-100 C2H2-type zinc finger
89-111 Zinc finger, C2H2 type
105-127 Zinc-finger double domain
117-139 Zinc finger, C2H2 type
117-139 C2H2-type zinc finger
117-137 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 GSKSFTCDQCGKYFSQKRQLKSHYRVHTGHSLPECSHCHRKFMDVSQLKKHLRTHTGEKP 60
61 FTCEICGKSFTAKSSLQTHIRIHRGEKPYSCSICGKCFSDSSAKRRHCILHTGKKPFSCP 120
121 ECGLQFARLDNLKAHLKIHSKEK
Interface Residues: 15, 16, 17, 18, 19, 22, 26, 43, 44, 45, 46, 47, 49, 50, 52, 53, 56, 61, 71, 72, 73, 74, 75, 77, 78, 79, 82, 99, 100, 101, 102, 103, 104, 105, 106, 107, 127, 128, 129, 130, 131, 133, 134, 137
3D-footprint Homologues: 5v3j_F, 5kkq_D, 1tf6_A, 5yel_A, 6wmi_A, 5ei9_F, 8ssq_A, 7w1m_H, 8ssu_A, 2i13_A, 3uk3_C, 8cuc_F, 7y3l_A, 7n5w_A, 4x9j_A, 5kl3_A, 5und_A, 1f2i_J, 6ml4_A, 2gli_A, 8gn3_A, 8h9h_G, 7eyi_G, 7y3m_I, 6e94_A, 7ysf_A, 2jpa_A, 1ubd_C, 2kmk_A, 6jnm_A, 1tf3_A, 6u9q_A, 1llm_D, 1mey_C, 5k5i_A, 1g2f_F, 6blw_A, 4m9v_C, 2lt7_A, 6a57_A, 7txc_E, 2wbs_A, 2drp_D, 5yj3_D
Binding Motifs: 6ml4_A CGTCCAGGACCTg
6ml6_A CGTCCAGGACCT
6ml7_A AGGTCCTGGAmGa
Binding Sites: 6ml4_E
6ml4_F
6ml6_F / 6ml7_F
6ml6_E
6ml7_E
Publications: Ren R, Hardikar S, Horton JR, Lu Y, Zeng Y, Singh AK, Lin K, Coletta LD, Shen J, Lin Kong CS, Hashimoto H, Zhang X, Chen T, Cheng X. Structural basis of specific DNA binding by the transcription factor ZBTB24. Nucleic Acids Res 47:8388-8398 (2019). [Pubmed]
Related annotations: PaperBLAST

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