Transcription Factor
| Accessions: | Q8IVH2 (JASPAR 2024) |
| Names: | Fork head-related protein-like A, Forkhead box protein P4, FOXP4_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q8IVH2 |
| Length: | 680 |
| Pfam Domains: | 467-546 Fork head domain |
| Sequence: (in bold interface residues) | 1 MMVESASETIRSAPSGQNGVGSLSGQADGSSGGATGTTASGTGREVTTGADSNGEMSPAE 60 61 LLHFQQQQALQVARQFLLQQASGLSSPGNNDSKQSASAVQVPVSVAMMSPQMLTPQQMQQ 120 121 ILSPPQLQALLQQQQALMLQQLQEYYKKQQEQLHLQLLTQQQAGKPQPKEALGNKQLAFQ 180 181 QQLLQMQQLQQQHLLNLQRQGLVSLQPNQASGPLQTLPQAAVCPTDLPQLWKGEGAPGQP 240 241 AEDSVKQEGLDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTVLTSRRDSSSHEETPGS 300 301 HPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLEIQLAKES 360 361 ERLQAMMAHLHMRPSEPKPFSQPLNPVPGSSSFSKVTVSAADSFPDGLVHPPTSAAAPVT 420 421 PLRPPGLGSASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYASLIRQAI 480 481 LETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKGAVWTVDE 540 541 REYQKRRPPKMTGSPTLVKNMISGLSYGALNASYQAALAESSFPLLNSPGMLNPGSASSL 600 601 LPLSHDDVGAPVEPLPSNGSSSPPRLSPPQYSHQVQVKEEPAEAEEDRQPGPPLGAPNPS 660 661 ASGPPEDRDLEEELPGEELS |
| Interface Residues: | 507, 510, 512, 513, 514, 516, 517, 518, 520, 521, 530, 532 |
| 3D-footprint Homologues: | 3l2c_A, 7vox_H, 2hdc_A, 2c6y_A, 7yzg_A, 7tdw_A, 3g73_A, 7yz7_A, 6el8_A, 7tdx_A, 7yzb_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 3qrf_G |
| Binding Motifs: | UN0537.1 rwGTAAACAdw MA2117.1 GTAAACA |
| Binding Sites: | MA2117.1.18 MA2117.1.13 / MA2117.1.14 / MA2117.1.15 / MA2117.1.3 / MA2117.1.8 / MA2117.1.9 UN0537.1.13 UN0537.1.3 UN0537.1.8 UN0537.1.9 UN0537.1.15 UN0537.1.16 UN0537.1.4 UN0537.1.6 UN0537.1.1 UN0537.1.5 UN0537.1.10 UN0537.1.11 UN0537.1.12 UN0537.1.14 UN0537.1.17 UN0537.1.18 UN0537.1.19 UN0537.1.2 UN0537.1.20 UN0537.1.7 MA2117.1.5 MA2117.1.16 MA2117.1.11 MA2117.1.1 MA2117.1.7 MA2117.1.12 / MA2117.1.17 MA2117.1.10 / MA2117.1.6 MA2117.1.2 / MA2117.1.4 MA2117.1.19 MA2117.1.20 |
| Publications: | Li S, Weidenfeld J, Morrisey EE. Transcriptional and DNA binding activity of the Foxp1/2/4 family is modulated by heterotypic and homotypic protein interactions. Mol Cell Biol 24:809-22 (2004). [Pubmed] |
| Related annotations: | PaperBLAST |
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