Transcription Factor
| Accessions: | 6cij_N (3D-footprint 20231221) |
| Names: | High mobility group protein 1, High mobility group protein B1, HMG-1, HMGB1_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Length: | 133 |
| Pfam Domains: | 1-62 Domain of unknown function (DUF1898) 5-67 HMG (high mobility group) box 69-133 Domain of unknown function (DUF1898) 72-133 HMG (high mobility group) box |
| Sequence: (in bold interface residues) | 1 PRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKKEKGKFEDMAKADKARYE 60 61 REKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAAKQPYE 120 121 KKAAKLKEKYEKD |
| Interface Residues: | 5, 8, 10, 11, 12, 18, 30, 34, 61, 64, 74, 77, 79, 80, 83, 87, 98, 99, 100, 103 |
| 3D-footprint Homologues: | 2gzk_A, 1ckt_A, 1o4x_B, 7m5w_A, 3f27_D, 4s2q_D, 1qrv_A, 3tmm_A, 4y60_C, 1j5n_A, 6jrp_D, 2lef_A, 3u2b_C, 1hry_A, 3tq6_B |
| Binding Motifs: | 6cij_CN ACnnnnnnnnnnnnnAAGTnnnnAnnnAG |
| Binding Sites: | 6cij_G 6cij_M |
| Publications: | Kim MS, Chuenchor W, Chen X, Cui Y, Zhang X, Zhou ZH, Gellert M, Yang W. Cracking the DNA Code for V(D)J Recombination. Mol Cell 70:358-370 (2018). [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.