Transcription Factor
| Accessions: | 6cij_N (3D-footprint 20231221) |
| Names: | High mobility group protein 1, High mobility group protein B1, HMG-1, HMGB1_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Length: | 133 |
| Pfam Domains: | 1-62 Domain of unknown function (DUF1898) 5-67 HMG (high mobility group) box 69-133 Domain of unknown function (DUF1898) 72-133 HMG (high mobility group) box |
| Sequence: (in bold interface residues) | 1 PRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKKEKGKFEDMAKADKARYE 60 61 REKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAAKQPYE 120 121 KKAAKLKEKYEKD |
| Interface Residues: | 5, 8, 10, 11, 12, 18, 30, 34, 61, 64, 74, 77, 79, 80, 83, 87, 98, 99, 100, 103 |
| 3D-footprint Homologues: | 2gzk_A, 1ckt_A, 3tmm_A, 4y60_C, 1j5n_A, 6jrp_D, 2lef_A, 3u2b_C, 1o4x_B, 7m5w_A, 3f27_D, 4s2q_D, 1qrv_A, 1hry_A, 3tq6_B |
| Binding Motifs: | 6cij_CN ACnnnnnnnnnnnnnAAGTnnnnAnnnAG |
| Binding Sites: | 6cij_G 6cij_M |
| Publications: | Kim MS, Chuenchor W, Chen X, Cui Y, Zhang X, Zhou ZH, Gellert M, Yang W. Cracking the DNA Code for V(D)J Recombination. Mol Cell 70:358-370 (2018). [Pubmed] |
| Related annotations: | PaperBLAST |
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