Transcription Factor

Accessions: UP00023A (UniPROBE 20160601)
Names: Sox30, SRY-box containing gene 30, Transcription factor SOX-30
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q8CGW4
Description: SRY-box containing gene 30: Mus musculus SRY-box containing gene 30 (Sox30)
Length: 101
Pfam Domains: 17-84 HMG (high mobility group) box
18-80 Domain of unknown function (DUF1898)
Sequence:
(in bold interface residues)
1 DAGIPDTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSE 60
61 EQKKPYYDEAQKIKEKHREEFPGWVYQPRPGKRKRFPLSVS
Interface Residues: 19, 22, 24, 25, 28, 32, 43, 44, 45, 47, 48, 51, 57, 86, 88, 90, 93
3D-footprint Homologues: 4y60_C, 2gzk_A, 1o4x_B, 6jrp_D, 2lef_A, 3u2b_C, 1qrv_A, 7m5w_A, 3f27_D, 4s2q_D, 3tmm_A, 1j5n_A, 3tq6_B, 1hry_A, 7zie_A, 1tau_A
Binding Motifs: UP00023A_1 rwdgAACAATkraayt
UP00023A_2 tmwgATTATAATmcgs
Binding Sites: AATTGTTG
AACAATAG
AACAATCA
AACAATGA
AACAATGC
AACAATGG
AACAATTA
AACAATTG
AAGACAAT
AATTGTTC
ACAACAAT
ACAATGGA
ACAATTGT
AGAACAAT
AGACAATG
ATTGTTAA
ATTGTTCG
ATTGTTGA
CAACAATG
CCATTGTC
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.