Transcription Factor
| Accessions: | 3l1p_B (3D-footprint 20231221) |
| Names: | NF-A3, Oct-3, Oct-4, Octamer-binding protein 3, Octamer-binding protein 4, Octamer-binding transcription factor 3, OTF-3, PO5F1_MOUSE, POU domain, class 5, transcription factor 1 |
| Organisms: | Mus musculus |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | P20263 |
| Length: | 145 |
| Pfam Domains: | 3-73 Pou domain - N-terminal to homeobox domain 88-144 Homeobox domain |
| Sequence: (in bold interface residues) | 1 KALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTISRFEALQLSLKNMSK 60 61 LRPLLEKWVEEADNNENLQEISKSQARKRKRTSIENRVRWSLETMFLKSPKPSLQQITHI 120 121 ANQLGLEKDVVRVWFSNRRQKGKRS |
| Interface Residues: | 25, 41, 42, 43, 44, 46, 47, 53, 57, 67, 70, 71, 74, 88, 89, 90, 91, 92, 129, 132, 133, 136, 137, 140, 141, 144 |
| 3D-footprint Homologues: | 7u0g_M, 3d1n_M, 3l1p_A, 1o4x_A, 7xrc_C, 1e3o_C, 8g87_X, 1au7_A, 2xsd_C, 5zfz_A, 2h1k_B, 6a8r_A, 2lkx_A, 1zq3_P, 1nk2_P, 2d5v_B, 1puf_B, 5hod_A, 1b72_A, 5jlw_D, 1ig7_A, 1le8_A, 7q3o_C, 3lnq_A, 6es3_K, 1du0_A, 4xrs_G, 3cmy_A, 1jgg_B, 3rkq_B, 1puf_A, 6m3d_C, 5flv_I, 5zjt_E, 4cyc_A, 2r5y_A, 1fjl_B, 2hdd_A, 4qtr_D, 2hos_A |
| Binding Motifs: | 3l1p_AB CATTTGCCTTTCAAATG |
| Binding Sites: | 3l1p_M 3l1p_N |
| Publications: | Esch D, Vahokoski J, Groves M.R, Pogenberg V, Cojocaru V, Vom Bruch H, Han D, Drexler H.C, Araúzo-Bravo M.J, Ng C.K, Jauch R, Wilmanns M, Schöler H.R. A unique Oct4 interface is crucial for reprogramming to pluripotency. Nature cell biology 15:295-301 (2013). [Pubmed] |
| Related annotations: | PaperBLAST |
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