Transcription Factor
| Accessions: | T154046_1.02 (CISBP 1.02), Q9FL26 (JASPAR 2024), T22946 (AthalianaCistrome v4_May2016) |
| Names: | T154046_1.02;, WRKY8, Probable WRKY transcription factor 8, WRKY DNA-binding protein 8, WRKY transcription factor 8, WRKY8_ARATH, AT5G46350, T22946; |
| Organisms: | Arabidopsis thaliana |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2, AthalianaCistrome v4_May2016 3 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] 3 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed] |
| Notes: | experiment type:PBM, family:WRKY, ecotype:Col-0, experiment type: ampDAP-seq, experiment type: ampDAP-seq (methyl-cytosines removed by PCR), experiment type: DAP-seq |
| Length: | 326 |
| Pfam Domains: | 183-240 WRKY DNA -binding domain |
| Sequence: (in bold interface residues) | 1 MSHEIKDLNNYHYTSSYNHYNINNQNMINLPYVSGPSAYNANMISSSQVGFDLPSKNLSP 60 61 QGAFELGFELSPSSSDFFNPSLDQENGLYNAYNYNSSQKSHEVVGDGCATIKSEVRVSAS 120 121 PSSSEADHHPGEDSGKIRKKREVRDGGEDDQRSQKVVKTKKKEEKKKEPRVSFMTKTEVD 180 181 HLEDGYRWRKYGQKAVKNSPYPRSYYRCTTQKCNVKKRVERSYQDPTVVITTYESQHNHP 240 241 IPTNRRTAMFSGTTASDYNPSSSPIFSDLIINTPRSFSNDDLFRVPYASVNVNPSYHQQQ 300 301 HGFHQQESEFELLKEMFPSVFFKQEP |
| Interface Residues: | 189, 190, 191, 193, 194, 205 |
| 3D-footprint Homologues: | 6j4f_F, 6j4g_B, 6ir8_A, 6j4e_B, 7z0u_A |
| Binding Motifs: | M1698_1.02 wrGTCAAmg MA1094.1 wrGTCAAmg M0792 raaAAAGTCAACgaw M0820 wwtcGTTGACTTTTt MA1094.2 waaAAAGTCAACghww MA1094.3 aAAAGTCAACg |
| Binding Sites: | MA1094.2.5 MA1094.2.7 MA1094.2.2 MA1094.2.3 MA1094.2.9 MA1094.2.10 MA1094.2.4 MA1094.2.1 MA1094.2.11 MA1094.2.12 MA1094.2.13 MA1094.2.14 MA1094.2.15 MA1094.2.16 MA1094.2.17 MA1094.2.18 MA1094.2.19 MA1094.2.20 MA1094.2.6 MA1094.2.8 MA1094.3.2 MA1094.3.1 MA1094.3.19 / MA1094.3.3 MA1094.3.16 / MA1094.3.4 / MA1094.3.6 MA1094.3.10 MA1094.3.12 MA1094.3.13 MA1094.3.14 MA1094.3.11 MA1094.3.15 MA1094.3.17 MA1094.3.18 MA1094.3.20 MA1094.3.5 MA1094.3.7 MA1094.3.8 MA1094.3.9 |
| Publications: | Yu D, Chen C, Chen Z. 2001. Evidence for an important role of WRKY DNA binding proteins in the regulation of NPR1 gene expression. Plant Cell. 13:1527-40. [Pubmed] |
| Related annotations: | PaperBLAST |
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