Transcription Factor

Accessions: 1ysa_D (3D-footprint 20231221)
Names: Amino acid biosynthesis regulatory protein, GCN4_YEAST, General control protein GCN4
Organisms: Saccharomyces cerevisiae, Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P03069
Length: 57
Pfam Domains: 3-55 bZIP transcription factor
3-53 Basic region leucine zipper
Sequence:
(in bold interface residues)
1 MKDPAALKRARNTEAARRSRARKLQRMKQLEDKVEELLSKNYHLENEVARLKKLVGE
Interface Residues: 8, 9, 11, 12, 13, 14, 15, 16, 19, 20
3D-footprint Homologues: 7x5e_F, 1nwq_C, 6mg1_B, 1llm_D, 2dgc_A, 5t01_B, 5vpe_D
Binding Motifs: 1ysa_CD TGAGTCA
1ysa_D TgAC
Binding Sites: 1ysa_A
1ysa_B
Publications: Ellenberger T., Brandl C. J., Struhl K., Harrison S. C. The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted helices: Crystal structure of the protein-DNA complex. Cell 71:1223-1237 (1992). [Pubmed]
Related annotations: PaperBLAST

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