Transcription Factor

Accessions: 6m3d_C (3D-footprint 20231221)
Names: HMEN_DROME, Segmentation polarity homeobox protein engrailed,Segmentation polarity homeobox protein engrailed
Organisms: Drosophila melanogaster
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P02836
Length: 108
Pfam Domains: 1-52 Homeobox domain
51-106 Homeobox domain
Sequence:
(in bold interface residues)
1 RTAFSSEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFKNKAARPRTAFSSEQ 60
61 LARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFKNKAAKIKKSG
Interface Residues: 1, 43, 46, 47, 50, 51, 52, 53, 54, 91, 92, 94, 95, 98, 99, 102, 103, 106
3D-footprint Homologues: 5zfz_A, 4j19_B, 6a8r_A, 6es3_K, 1o4x_A, 1le8_B, 2lkx_A, 6m3d_C, 1nk2_P, 1zq3_P, 1jgg_B, 3lnq_A, 1puf_A, 1b72_A, 4cyc_A, 1ig7_A, 5flv_I, 3d1n_M, 2hdd_A, 5zjt_E, 2r5y_A, 7psx_B, 5hod_A, 2hos_A, 3a01_E, 2d5v_B, 7q3o_C, 1au7_A, 5jlw_D, 3rkq_B, 2ld5_A, 1fjl_B, 4xrs_G, 3cmy_A, 2h1k_B, 1mnm_C, 1e3o_C, 1puf_B, 1du0_A, 4qtr_D, 8g87_X
Binding Motifs: 6m3d_C CyAATCc
Binding Sites: 6m3d_A
6m3d_B
Publications: Sunami T, Hirano Y, Tamada T, Kono H. Structural basis for designing an array of engrailed homeodomains. Acta Crystallogr D Struct Biol : (2020). [Pubmed]
Related annotations: PaperBLAST

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