Transcription Factor
Accessions: | CEBPD_HUMAN (HOCOMOCO 10), P49716 (JASPAR 2024) |
Names: | C/EBP delta, CCAAT/enhancer-binding protein delta, CEBPD_HUMAN, Nuclear factor NF-IL6-beta |
Organisms: | Homo sapiens |
Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Uniprot: | P49716 |
Length: | 269 |
Pfam Domains: | 191-242 Basic region leucine zipper 196-247 bZIP transcription factor |
Sequence: (in bold interface residues) | 1 MSAALFSLDGPARGAPWPAEPAPFYEPGRAGKPGRGAEPGALGEPGAAAPAMYDDESAID 60 61 FSAYIDSMAAVPTLELCHDELFADLFNSNHKAGGAGPLELLPGGPARPLGPGPAAPRLLK 120 121 REPDWGDGDAPGSLLPAQVAACAQTVVSLAAAGQPTPPTSPEPPRSSPRQTPAPGPAREK 180 181 SAGKRGPDRGSPEYRQRRERNNIAVRKSRDKAKRRNQEMQQKLVELSAENEKLHQRVEQL 240 241 TRDLAGLRQFFKQLPSPPFLPAAGTADCR |
Interface Residues: | 197, 198, 200, 201, 202, 204, 205, 208, 209, 223, 236 |
3D-footprint Homologues: | 1gd2_G, 2wt7_A, 1nwq_C, 6mg1_B, 5t01_B, 2c9l_Z, 2dgc_A, 7yq3_E |
Binding Motifs: | MA0836.1 rTTrCGCAAy UN0523.1 rsCGGAwrTTGCGyAAy CEBPD_HUMAN.H10MO.B|M01050 rrTkryGcAAt MA0836.2 krTTGCACAAyww MA0836.3 TTGCACAA UN0523.2 sCGGAwrTTGCGyAAy |
Binding Sites: | MA0836.3.1 / MA0836.3.7 MA0836.2.1 MA0836.2.10 MA0836.2.11 MA0836.2.12 / MA0836.2.13 MA0836.2.13 / MA0836.2.14 MA0836.2.14 / MA0836.2.15 MA0836.2.15 MA0836.2.16 MA0836.2.17 MA0836.2.16 / MA0836.2.18 MA0836.2.17 / MA0836.2.19 MA0836.2.2 MA0836.2.20 MA0836.2.3 MA0836.2.4 MA0836.2.3 / MA0836.2.5 MA0836.2.5 / MA0836.2.6 MA0836.2.6 / MA0836.2.7 MA0836.2.7 / MA0836.2.8 MA0836.2.9 MA0836.2.12 MA0836.2.18 MA0836.2.19 MA0836.2.2 MA0836.2.20 MA0836.2.4 MA0836.2.8 MA0836.3.10 / MA0836.3.18 / MA0836.3.19 / MA0836.3.5 / MA0836.3.6 / MA0836.3.9 MA0836.3.11 / MA0836.3.13 MA0836.3.12 / MA0836.3.8 MA0836.3.14 MA0836.3.15 MA0836.3.16 MA0836.3.17 MA0836.3.2 MA0836.3.20 / MA0836.3.4 MA0836.3.3 |
Publications: | Osada S, Yamamoto H, Nishihara T, Imagawa M. DNA binding specificity of the CCAAT/enhancer-binding protein transcription factor family. J Biol Chem 271:3891-6 (1996). [Pubmed] |
Related annotations: | PaperBLAST |
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