Transcription Factor

Accessions: T015185_1.02 (CISBP 1.02)
Names: T015185_1.02;, Tcfec
Organisms: Mus musculus
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:bHLH
Length: 317
Pfam Domains: 111-164 Helix-loop-helix DNA-binding domain
196-315 Domain of unknown function (DUF3371)
Sequence:
(in bold interface residues)
1 MTFDCRVCDQTLKRAQPPAASCMPLAEHEPMSPDSDAGCAGNPFTNLLALGKKDGAEKWH 60
61 LSGSILDVYSDEQGISSANAGLTDAPCPSILPMRKEIAETDGRALAKERQKKDNHNLIER 120
121 RRRYNINYRIKELGTLIPKSNDPDMRWNKGTILKASVDYIKWLQKEQQRARELEHRQKKL 180
181 EHANRQLRLRIQELEIQARAHGLPILASLGTADVGTHITKQQTHPERNLGGCCLQLTPTQ 240
241 GTSPEFYEQAVAFSDPLSHFTDLSFSAALKEEQRLDGMLLSDTICPFGTDPLLSAISPAV 300
301 SKASSRSSLSSEDGDEL
Interface Residues: 112, 114, 115, 116, 118, 119, 122, 123, 147, 149
3D-footprint Homologues: 1a0a_B, 1an4_A, 4h10_A, 7d8t_A, 5gnj_I, 8osl_O, 5v0l_A, 4h10_B, 7f2f_B, 5i50_B, 4zpk_A, 7ssa_L, 6g1l_A, 5eyo_A, 1am9_A, 7xi3_A, 5nj8_D, 2ypa_A, 8osl_P, 2ypa_B, 5nj8_C, 5v0l_B
Binding Motifs: M0201_1.02 rtCaCGtGay
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.