Transcription Factor

						

			
Accessions: UP00082A (UniPROBE 20160601)

			
Names: Not Available, Zfp187, zinc finger protein 187
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q5RJ54
Description: zinc finger protein 187: Mus musculus zinc finger protein 187
Length: 212
Pfam Domains:     16-36 C2H2-type zinc finger
    16-38 C2H2-type zinc finger
    16-38 Zinc finger, C2H2 type
    30-54 Zinc-finger double domain
    44-66 Zinc finger, C2H2 type
    44-58 C2H2-type zinc finger
    44-66 C2H2-type zinc finger
    59-82 Zinc-finger double domain
    72-94 C2H2-type zinc finger
    74-94 Zinc finger, C2H2 type
   86-111 Zinc-finger double domain
  100-122 C2H2-type zinc finger
  101-122 Zinc finger, C2H2 type
  102-122 C2H2-type zinc finger
  115-138 Zinc-finger double domain
  128-148 C2H2-type zinc finger
  128-150 Zinc finger, C2H2 type
  128-146 C2H2-type zinc finger
  143-165 Zinc-finger double domain
  156-178 C2H2-type zinc finger
  156-178 Zinc finger, C2H2 type
  156-166 C2H2-type zinc finger
  170-194 Zinc-finger double domain
  183-208 C2H2-type zinc finger
  184-207 C2H2-type zinc finger
  184-206 Zinc finger, C2H2 type
Sequence: 
(in bold interface residues)		   1 SSVAADHQEISKDKGHPCQECGKVFQRSSHLIRHQKIHLGEKPYQCKECGKVFSQNAGLL   60
  61 EHLRIHTGEKPYLCIHCGKNFRQSSHLNRHQKIHSQDEPRECKECGKTFSRALLLTHHQR  120
 121 VHGRSKRHHCNECGKAFSLTSDLIRHHRIHTGEKPFKCNVCQKAFRLNSHLDQHVRIHNE  180
 181 EKPYKCSECNEAFRQKSGLFQHQRHHHKSKLA
Interface Residues: 26, 27, 28, 29, 30, 32, 33, 35, 36, 37, 39, 54, 55, 56, 57, 58, 60, 61, 62, 82, 83, 84, 85, 86, 87, 88, 89, 90, 93, 110, 111, 112, 113, 114, 115, 116, 117, 138, 139, 140, 141, 142, 144, 145, 151, 157, 165, 166, 167, 168, 169, 170, 171, 172, 173, 177, 194, 195, 196, 197, 198, 200, 201, 205
3D-footprint Homologues: 7n5w_A, 6jnm_A, 2kmk_A, 7ysf_A, 6blw_A, 5kkq_D, 8ssq_A, 2gli_A, 7w1m_H, 1g2f_F, 5ei9_F, 1tf6_A, 5kl3_A, 8ssu_A, 2i13_A, 5k5i_A, 1ubd_C, 1mey_C, 1f2i_J, 4x9j_A, 7eyi_G, 8h9h_G, 6wmi_A, 2lt7_A, 6a57_A, 2jpa_A, 1llm_D, 2wbs_A, 8gn3_A, 5und_A, 2drp_D, 7txc_E, 4m9v_C, 7y3m_I, 5yel_A, 6ml4_A, 5yj3_D, 5v3j_F, 6rnr_A, 6fl1_A, 4pd2_A, 6e94_A, 1tf3_A, 8cuc_F, 7y3l_A, 6u9q_A, 3jso_B, 3uk3_C, 5k5l_F
Binding Motifs: UP00082A_1 ytATGTACyAATwm
UP00082A_2 grrmCCTtGTyCmywv
Binding Sites: AATTAATA
AGTACATA
ATGTACTA
ATTAACAC
ATTAATAC
ATTAGCAC
ATTAGTAC
ATTAGTCC
ATTGGCAC
ATTGGTAC
CCTGGTCC
CCTTGTCC
CCTTGTTC
TATTAATA
TGTACCAA
TGTACTAA
TGTATTAA
TGTGCCAA
TGTGCTAA
TGTGTTAA
			
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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