Transcription Factor

						

			
Accessions: T152781_1.02 (CISBP 1.02)

			
Names: PRKRIR, T152781_1.02;
Organisms: Gallus gallus
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:THAP finger
Length: 767
Pfam Domains:      4-88 THAP domain
  159-335 Domain of unknown function (DUF4371)
  637-729 hAT family dimerisation domain
Sequence: 
(in bold interface residues)		   1 MPNFCAAPNCTRKSTQSDLAFFRFPRDPVRCQRWVENCRRADLEDKTPDQLNKHYRLCAK   60
  61 HFETSMICRSSPYRTVLRDNAVPTIFDLTSHLNNPHSRHRKRIKELSEDEIRTLKQQKIN  120
 121 EAFEREQATQELNESNAQNAVSEEGGEQQEEKSVPLTLEERENKDYLKSLFEILILMGKQ  180
 181 NIPLDSHNADELPEGIFTSDNFQALLEYRINAGDEVLRKRFEMTAVNLEYCSKTQQKQML  240
 241 EICESCIREETLREVRDSHFFSIVTDEVVDIAGEEHLPVLVRFVDDSHNLREEFIGFLPY  300
 301 EADPEILAVKFHTTITEKWGLNMEYCRGQAYIVSSGFASKMKVVATRLLEKYPQAVYTLC  360
 361 SSCALNVWLAKSVPVVGVSMALGTIEEVRCLFSRSPQLLVELDNTISALFQNNEEKGNEL  420
 421 KEICRSQWTGRHDTFEVLVDLMQALVLCLDAVSNDSTVRWNNFIAGRAFVLSSALTDFDF  480
 481 IVTIVILKNVLSFTRAFGKNLQGQTSDIFFAASSLTAVLHSLNEVMENIEVYHEFWFEEA  540
 541 TNLAAKLDVQIKLPGKFRRSQQGNLDAELTSENYYKEILSVPTVEHIIQELKDIFSEQHL  600
 601 KALKCLSLVPSVMGQLKFNTSEEHHADMYKNDLPNPDTLSAELHCWRIKWKHRGKDIELP  660
 661 ATIYEALHLPDIKYFPNVYALLKVLCILPVMKVENEKYEVGRKRLKAYLKNTVTEQRSSN  720
 721 LALLNINIDIKHDLDLMVDTYIKLYPGKVEFQADFLPSNNSEVTESA
Interface Residues: 23, 45, 52, 54, 55, 56, 69, 580, 581, 582, 583, 585
3D-footprint Homologues: 2ko0_A, 6fix_D
Binding Motifs: M1669_1.02 gtcCCkGgctww
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.