Transcription Factor
| Accessions: | P17023 (JASPAR 2024) |
| Names: | Zinc finger protein 19, Zinc finger protein KOX12, ZNF19_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P17023 |
| Length: | 458 |
| Pfam Domains: | 14-54 KRAB box 161-183 Zinc finger, C2H2 type 161-183 C2H2-type zinc finger 161-173 C2H2-type zinc finger 176-198 Zinc-finger double domain 188-209 C2H2-type zinc finger 189-211 Zinc finger, C2H2 type 189-211 C2H2-type zinc finger 204-227 Zinc-finger double domain 217-239 Zinc finger, C2H2 type 217-239 C2H2-type zinc finger 217-237 C2H2-type zinc finger 231-256 Zinc-finger double domain 245-267 C2H2-type zinc finger 245-265 C2H2-type zinc finger 245-267 Zinc finger, C2H2 type 261-283 Zinc-finger double domain 272-282 C2H2-type zinc finger 273-295 Zinc finger, C2H2 type 288-311 Zinc-finger double domain 300-321 C2H2-type zinc finger 301-323 C2H2-type zinc finger 301-323 Zinc finger, C2H2 type 315-338 Zinc-finger double domain 329-351 Zinc finger, C2H2 type 329-351 C2H2-type zinc finger 329-349 C2H2-type zinc finger 344-367 Zinc-finger double domain 357-379 Zinc finger, C2H2 type 357-379 C2H2-type zinc finger 372-393 Zinc-finger double domain 385-407 Zinc finger, C2H2 type 385-407 C2H2-type zinc finger 400-424 Zinc-finger double domain |
| Sequence: (in bold interface residues) | 1 MAAMPLKAQYQEMVTFEDVAVHFTKTEWTGLSPAQRALYRSVMLENFGNLTALGYPVPKP 60 61 ALISLLERGDMAWGLEAQDDPPAERTKNVCKDVETNIDSESTLIQGISEERDGMMSHGQL 120 121 KSVPQRTDFPETRNVEKHQDIPTVKNIQGKVPRIPCARKPFICEECGKSFSYFSYYARHQ 180 181 RIHTGEKPFECSECGKAFNGNSSLIRHQRIHTGERPYQCEECGRAFNDNANLIRHQRIHS 240 241 GDRPYYCTECGNSFTSSSEFVIHQRIHTGEKPYECNECGKAFVGNSPLLRHQKIHTGEKP 300 301 YECNECGKSFGRTSHLSQHQRIHTGEKPYSCKVCGQAFNFHTKLTRHQRIHSEEKPFDCV 360 361 DCGKAFSAQEQLKRHLRIHTQESSYVCDECGKALTSKRNLHQHQRIHTGEKPYECSKYEK 420 421 AFGTSSQLGHLEHVYSGEKPVLDICRFGLPEFFTPFYW |
| Interface Residues: | 161, 172, 173, 174, 175, 178, 182, 199, 200, 201, 202, 203, 206, 207, 227, 228, 229, 230, 231, 232, 233, 234, 235, 255, 256, 257, 258, 259, 261, 262, 264, 265, 266, 268, 283, 284, 285, 286, 287, 289, 290, 294, 311, 312, 313, 314, 315, 318, 340, 341, 342, 343, 344, 345, 346, 367, 368, 369, 370, 371, 373, 374, 377, 380, 382, 394, 395, 396, 398, 399, 402, 406, 424, 426, 427, 430 |
| 3D-footprint Homologues: | 2kmk_A, 8ssq_A, 8ssu_A, 5no6_N, 7ysf_A, 6a57_A, 6jnm_A, 3uk3_C, 7y3l_A, 1tf6_A, 5ei9_F, 7w1m_H, 5k5i_A, 4m9v_C, 7y3m_I, 6e94_A, 5v3j_F, 7txc_E, 6ml4_A, 1g2f_F, 5yel_A, 1ubd_C, 8cuc_F, 5k5l_F, 6blw_A, 2jpa_A, 7n5w_A, 1tf3_A, 4x9j_A, 2gli_A, 1f2i_J, 5kkq_D, 2wbs_A, 5kl3_A, 5yj3_D, 8h9h_G, 2lt7_A, 6u9q_A, 1llm_D, 2drp_D, 8gn3_A, 6dta_B |
| Binding Motifs: | UN0599.1 srgsgkkGywRGGgyycTGACgks UN0599.2 kgywrGGgyycTGACg |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.