Transcription Factor

						

			
Accessions: T134155_1.02 (CISBP 1.02)

			
Names: nhr-177, T134155_1.02;
Organisms: Caenorhabditis elegans
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:Nuclear receptor
Length: 421
Pfam Domains:    33-102 Zinc finger, C4 type (two domains)
  202-400 Ligand-binding domain of nuclear hormone receptor
Sequence: 
(in bold interface residues)		   1 MKNLINICPRPSTSNHFSNISLSSSEPPPPRKDCRICFEKGHGYHFGVFSCRACAAFFRR   60
  61 CHFLKENRRRCRLSKGKCGPNKNGKWFCKTCRLERCFRLGMTPSNIQYDRDAYKSSVKKI  120
 121 KDSAENITEPKRDATSLILINKTSQVLPYVDLSQLVNKATRMLLNPIFTKKTKKMSNLEQ  180
 181 LTHGLIELQWSQKDNLAEVVHLSVSDVTQDMERSMFGAAKWMMCSERIRNYQDSLKIRIL  240
 241 QAIWYTWGRLERIATTAKLRLEKKCEEKHFVFSPMFALNLDEMSFDASCWTTLPFEEMQY  300
 301 FYVPRELFYEDAVLEMMEVKPNDVETTFIICSICFHLTGKRFGGEIQEKMDHLQDVLSND  360
 361 LHEYYLKNKNSMYLRRLKQLMRIKENFLKLRSARMDKYEIGGFFNSFNPRISNPEFFEVL  420
 421 S
Interface Residues: 42, 43, 45, 46, 52, 53, 55, 56, 59, 60, 86, 108, 110
3D-footprint Homologues: 6fbq_A, 7wnh_D, 6l6q_B, 3g9m_B, 1a6y_A, 1lo1_A, 4oln_B, 8cef_H, 5krb_G, 2han_B, 1kb2_B, 2a66_A, 8hbm_B, 2nll_B, 1lat_A, 7xv6_B, 2ff0_A, 1dsz_A, 4umm_E, 3cbb_A, 7xvn_C, 4iqr_B, 2han_A, 1hcq_E, 7prw_B, 5cbx_B, 3g6t_A, 1r4i_A, 5cbz_E, 4tnt_B, 5e69_A, 4hn5_B, 8rm6_A, 5emc_A
Binding Motifs: M1462_1.02 rhTCyCGA
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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