Transcription Factor

Accessions: P19793 (JASPAR 2024)
Names: Nuclear receptor subfamily 2 group B member 1, Retinoic acid receptor RXR-alpha, Retinoid X receptor alpha, RXRA_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P19793
Length:
Binding Motifs: MA0074.1 RGGTCAwcGrGTTCA
MA0159.1 rGkTCAysgrsAGKTCA
MA0115.1 AAAGGTCAAAGGTCAAc
MA1146.1 grGkTCAtTGACCyy
MA1147.1 rrGGTCrtTGACCyc
MA1148.1 awgtrGGtcAaAGGTcAt
Binding Sites: MA0074.1.1
MA0074.1.10
MA0074.1.2
MA0074.1.3
MA0074.1.4
MA0074.1.5
MA0074.1.6
MA0074.1.7
MA0074.1.8
MA0074.1.9
MA0115.1.1 / MA0115.1.10 / MA0115.1.2 / MA0115.1.3 / MA0115.1.4 / MA0115.1.5 / MA0115.1.6 / MA0115.1.7 / MA0115.1.8 / MA0115.1.9
MA0115.1.11
MA0115.1.12
MA0115.1.13
MA0115.1.14
MA0115.1.15
MA0115.1.16
MA0115.1.17
MA0115.1.18
MA0115.1.19 / MA0115.1.20
MA0159.1.1
MA0159.1.10
MA0159.1.11
MA0159.1.12
MA0159.1.13
MA0159.1.14
MA0159.1.15
MA0159.1.16
MA0159.1.17
MA0159.1.18
MA0159.1.19
MA0159.1.2
MA0159.1.20
MA0159.1.3
MA0159.1.4
MA0159.1.5
MA0159.1.6
MA0159.1.7
MA0159.1.8
MA0159.1.9
Publications: Laffitte B. A., Kast H. R., Nguyen C. M., Zavacki A. M., Moore D. D., Edwards P. A. Identification of the DNA binding specificity and potential target genes for the farnesoid X-activated receptor.. J. Biol. Chem. 275:10638-10647 (2000). [Pubmed]

Feltkamp D., Wiebel F. F., Alberti S., Gustafsson J. A. Identification of a novel DNA binding site for nuclear orphan receptor OR1. J. Biol. Chem. 274:10421-10429 (1999). [Pubmed]

Portales-Casamar E, Kirov S, Lim J, Lithwick S, Swanson M.I, Ticoll A, Snoddy J, Wasserman W.W. PAZAR: a framework for collection and dissemination of cis-regulatory sequence annotation. Genome biology 8:R207 (2007). [Pubmed]

Colnot S, Lambert M, Blin C, Thomasset M, Perret C. Identification of DNA sequences that bind retinoid X receptor-1,25(OH)2D3-receptor heterodimers with high affinity. Molecular and cellular endocrinology 113:89-98 (1995). [Pubmed]

Perlmann T., Jansson L. A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1. Genes Dev. 9:769-782 (1995). [Pubmed]

Bardot O, Aldridge TC, Latruffe N, Green S. PPAR-RXR heterodimer activates a peroxisome proliferator response element upstream of the bifunctional enzyme gene. Biochem Biophys Res Commun 192:37-45 (1993). [Pubmed]
Related annotations: PaperBLAST

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